Evidence map›Paper›PMID 35495178›Full record

ArticleCase reports in hematology2022

Concurrent B Cell Acute Lymphoblastic Lymphoma/Leukemia and Monoclonal B Cell Lymphocytosis: A Case Report with Extensive Molecular Analysis.

Maryam Mehdipour Dalivand, Parastou Tizro, Julie Partain, Anita Aggarwal, Jack Lichy, Francisco Mot Ara, Victor E Nava

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Maryam Mehdipour DalivandThe George Washington University, Department of Pathology, Washington, DC, USA.ORCID https://orcid.org/0000-0003-2671-6325
Parastou TizroThe George Washington University, Department of Pathology, Washington, DC, USA.
Julie PartainOregon Health and Science University, Portland, OR, USA.
Anita AggarwalThe George Washington University, Department of Medicine, Hematology and Oncology, Washington, DC, USA.
Jack LichyThe George Washington University, Department of Pathology, Washington, DC, USA.
Francisco Mot AraHospital J.M. de Los Rios, Department of Pathology, Caracas, Venezuela.
Victor E NavaThe George Washington University, Department of Pathology, Washington, DC, USA.ORCID https://orcid.org/0000-0002-1438-9665
United States Department of Veterans Affairs · USGeorge Washington University · USHospital Clínico Universitario de Caracas · VEOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although acute lymphoblastic leukemia (ALL) and monoclonal B cell lymphocytosis (MBL) are common neoplasia, a simultaneous presentation is very unusual. Here, we present two different B cell clones, MBL and B-ALL, cocirculating in a 78-year-old African American male. Detailed molecular characterization revealed an unusual MPL (T487I) point mutation and unmutated VH4-39. After nonstandard chemotherapy, the patient remains in morphologic remission. These findings may stimulate further research to clarify the pathogenesis of hematologic neoplasms.

Identifiers

PMID35495178
PMCPMC9050327
OpenAlexW4224266997

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.