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ArticleFrontiers in genetics2022

Interest in Cancer Predisposition Testing and Carrier Screening Offered as Part of Routine Healthcare Among an Ethnically Diverse Sample of Young Women.

Kimberly A Kaphingst, Jemar R Bather, Brianne M Daly, Daniel Chavez-Yenter, Alexis Vega, Wendy K Kohlmann

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07052266 (Feasibility of Obstetric and Cancer Universal Screening), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07052266 narecruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility of Obstetric and Cancer Universal Screening

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2025 to 2028Enrolled550ConditionsHereditary Cancer SyndromesArmsMyRisk Hereditary Cancer Test
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kimberly A KaphingstDepartment of Communication, University of Utah, Salt Lake City, UT, United States.
Jemar R BatherDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Brianne M DalyHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States.
Daniel Chavez-YenterDepartment of Communication, University of Utah, Salt Lake City, UT, United States.
Alexis VegaDepartment of Communication, University of Utah, Salt Lake City, UT, United States.
Wendy K KohlmannHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States.
Huntsman Cancer Institute · USUniversity of Utah · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sequencing technologies can inform individuals' risks for multiple conditions, supporting population-level screening approaches. Prior research examining interest in genetic testing has not generally examined the context of population-based approaches offered in routine healthcare or among ethnically diverse populations. Cancer predisposition testing and carrier screening could be offered broadly to women of reproductive age. This study therefore examined interest in these tests when offered as part of routine care, and predictors of interest, among an ethnically diverse sample of women aged 20-35. We conducted an online English-language survey of 450 women; 39% identified as Latina. We examined predictors of interest for two outcomes, interest in testing in the next year and level of interest, in multivariable logistic regression models and stratified analyses by Latina ethnicity. More than half of respondents reported being interested in cancer predisposition testing (55%) and carrier screening (56%) in the next year; this did not differ by ethnicity. About 26% reported being very interested in cancer predisposition testing and 27% in carrier screening. Latina respondents (32%) were more likely to be very interested in cancer predisposition testing than non-Latina respondents (22%;

Indexed as

cancer predisposition testingcarrier screeningethnicitygenetic testingpopulation screening

Identifiers

PMID35495140
PMCPMC9047995
OpenAlexW4223904783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.