Evidence map›Paper›PMID 35495045›Full record

ArticleFrontiers in neuroscience2022

Functional Connectivity Underlying Symptoms in Preschool Boys With Autism: A Resting-State Functional Magnetic Resonance Imaging Study.

Zhihong Lan, Shoujun Xu, Xiangrong Yu, Zhenjie Yu, Meng Li, Feng Chen, Yu Liu, Tianyue Wang, Yunfan Wu, Yungen Gan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zhihong LanDepartment of Medical Imaging, Zhuhai People's Hospital, Zhuhai Hospital Affiliated With Jinan University, Zhuhai, China.
Shoujun XuDepartment of Radiology, Shenzhen Children's Hospital, Shenzhen, China.
Xiangrong YuDepartment of Medical Imaging, Zhuhai People's Hospital, Zhuhai Hospital Affiliated With Jinan University, Zhuhai, China.
Zhenjie YuDepartment of Medical Imaging, Zhuhai People's Hospital, Zhuhai Hospital Affiliated With Jinan University, Zhuhai, China.
Meng LiDepartment of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou, China.
Feng ChenDepartment of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou, China.
Yu LiuDepartment of Medical Imaging, Zhuhai People's Hospital, Zhuhai Hospital Affiliated With Jinan University, Zhuhai, China.
Tianyue WangDepartment of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou, China.
Yunfan WuDepartment of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou, China.
Yungen GanDepartment of Radiology, Shenzhen Children's Hospital, Shenzhen, China.
Guihua JiangDepartment of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou, China.
Guangdong Provincial People's Hospital · CNZhuhai People's Hospital · CNShenzhen Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Single-sex children have been regarded as one of the best subjects to understand the abnormal development patterns of autism spectrum disorders (ASDs). However, the functional connectivity (FC) behind their symptoms is still unknown. Methods: Based on FC analysis, the acquired resting-state functional magnetic resonance imaging (rs-fMRI) data sets, including 86 boys with ASD and 54 normal controls (NC), were used to detect the neural synchronous activity between brain regions. Pearson correlation analysis was used to evaluate the relationship between the abnormal FC value and clinical features. Results: Individuals with ASD showed enhanced FC between the right calcarine and the right lingual gyrus (LG). The right medial orbital frontal cortex also showed increased FC with bilateral inferior temporal gyrus (ITG) [two-tailed, voxel-level Conclusion: Our study reveals a possible relationship between atypical visual attention and poor learning ability in subjects with ASD, and delayed social language development may be a secondary symptom to ASD.

Indexed as

autism spectrum disordersfunctional connectivitypreschool boysresting-state fMRIvisual

Identifiers

PMID35495045
PMCPMC9047045
OpenAlexW4224109484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.