ReviewCureus2022
Does Insufficient Sleep Increase the Risk of Developing Insulin Resistance: A Systematic Review.
Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Impact of automated insulin delivery on subjective and objective sleep in children and young adults with very high HbA1c: Sleep outcomes from the CO-PILOT randomised controlled trial.Diabetic medicine : a journal of the British Diabetic Association · 2025Trial
- Trial
- Sleep Quality by Reproductive Stage Among Women Living With HIV in the United States Enrolled in the Health Outcomes Around Pregnancy and Exposure to HIV/Antiretrovirals (HOPE) Study.Journal of acquired immune deficiency syndromes (1999) · 2026Observational
- Potential of Triazines as Antidiabetic Agents-A Review of Structures and Pharmacological Activity.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Insulin Resistance as a Systemic Metabolic Risk State for Cancer: Mechanisms, Biomarkers, and Prevention.International journal of molecular sciences · 2026Review
- Physical activity, sedentary behaviour, and anthropometric profiles in women with and without insulin resistance: a cross-sectional study.BMC women's health · 2026Article
- The Natural History of Prediabetes and Cardiovascular Disease in the Pediatric Population.Biomedicines · 2026Review
- Daytime sleepiness and specific food cravings: The moderating role of insulin sensitivity.PloS one · 2026Article
- Is Insulin Resistance the Driver or the Outcome of Diabetes Mellitus? A Critical Review.Journal of nutrition and metabolism · 2026Review
- Metabolic status and brain health: the relationship between the metabolic score for insulin resistance and cognitive function in older adults.European journal of medical research · 2025Article
- Can weekend catch-up sleep repay the sleep debt? Balancing short-term relief with long-term risks.Sleep & breathing = Schlaf & Atmung · 2025Review
- Insomnia and sleepiness during pregnancy: Associations with gestational diabetes mellitus.Acta obstetricia et gynecologica Scandinavica · 2025Article
- The pulse of sleep: novel interventions in understanding the sleep-cardiovascular connection: a literature review.Annals of medicine and surgery (2012) · 2024Review
- Associations of actigraphy-assessed sleep variables with adiposity and serum cardiometabolic outcomes in emerging adults.Journal of sleep research · 2024Article
- Review
- Association between sleep problems and multimorbidity patterns in older adults.BMC public health · 2023Article
- Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005-2016.Frontiers in nutrition · 2023Article
- Sleep behavior and daily activity levels in people with metabolic syndrome: effect of 1 year of metformin treatment.Frontiers in nutrition · 2023Article
- Sleep Quality and Its Associated Factors among Adult Patients Admitted in the Intensive Care Units of Public Hospitals in Addis Ababa, Ethiopia.SAGE open nursingArticle
- Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery.The Journal of cardiovascular nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been recommended that adults sleep a minimum of seven hours of sleep every night to maintain holistic health and well-being. A considerable fraction of the adult population suffers from sleep deprivation and related disorders. The stress of modern-day living may be the cause of this curtailment of sleep duration. The primary purpose of this study was to investigate the effects of reduced sleep on the development of insulin resistance and explore the possible mechanisms linking the two. We utilized databases like such as PubMed, PubMed Central (PMC), and Medical Literature Analysis and Retrieval System Online (MEDLINE) to systematically screen papers using keywords and Medical Subject Heading (MeSH) terms. A few articles were also retrieved from Cochrane Library. We applied inclusion/exclusion criteria after screening papers via title and abstracts. A quality appraisal check was doneperformed, and ten 10 related studies were strictly reviewed. Short sleep duration was significantly associated with insulin resistance. Inflammatory markers such as C-reactive protein (CRP) and serum amyloid A (SAA), biomarkers such as glucagon-like peptide-1 (GLP-1), and circadian misalignment may play a significant role in the pathogenesis of this association. To prevent metabolic complications such as type- 2 diabetes, adequate sleep (more than seven hours per night) is required in the adult population. The causal relationship between sleep deprivation and insulin resistance is multifactorial, and further studies are warranted to understand these mechanisms better.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.