Evidence map›Paper›PMID 35494782›Full record

ArticleRSC advances2021

A novel characterisation approach to reveal the mechano-chemical effects of oxidation and dynamic distension on polypropylene surgical mesh.

Nicholas T H Farr, Sabiniano Roman, Jan Schäfer, Antje Quade, Daniel Lester, Vanessa Hearnden, Sheila MacNeil, Cornelia Rodenburg

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  6. Characterization in respect to degradation of titanium-coated polypropylene surgical mesh explanted from humans.Journal of biomedical materials research. Part B, Applied biomaterials · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Nicholas T H FarrDepartment of Materials Science and Engineering, University of Sheffield Sir Robert Hadfield Building, Mappin Street UK n.t.farr@sheffield.ac.uk.ORCID https://orcid.org/0000-0001-6761-3600
Sabiniano RomanDepartment of Materials Science and Engineering, University of Sheffield Sir Robert Hadfield Building, Mappin Street UK n.t.farr@sheffield.ac.uk.ORCID https://orcid.org/0000-0002-2368-7955
Jan SchäferLeibniz Institute for Plasma Science and Technology (INP e.V.) Felix-Hausdorff-Str. 2 17489 Greifswald Germany.ORCID https://orcid.org/0000-0002-0652-5057
Antje QuadeLeibniz Institute for Plasma Science and Technology (INP e.V.) Felix-Hausdorff-Str. 2 17489 Greifswald Germany.ORCID https://orcid.org/0000-0003-0814-4319
Daniel LesterPolymer Characterisation Research Technology Platform, University of Warwick Library Road CV4 7AL Coventry UK.
Vanessa HearndenDepartment of Materials Science and Engineering, University of Sheffield Sir Robert Hadfield Building, Mappin Street UK n.t.farr@sheffield.ac.uk.ORCID https://orcid.org/0000-0003-0838-7783
Sheila MacNeilDepartment of Materials Science and Engineering, University of Sheffield Sir Robert Hadfield Building, Mappin Street UK n.t.farr@sheffield.ac.uk.
Cornelia RodenburgDepartment of Materials Science and Engineering, University of Sheffield Sir Robert Hadfield Building, Mappin Street UK n.t.farr@sheffield.ac.uk.ORCID https://orcid.org/0000-0002-9590-375X
University of Sheffield · GBLeibniz Institute for Plasma Science and Technology · DEInsigneo · GBUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polypropylene (PP) surgical mesh, used successfully for the surgical repair of abdominal hernias, is associated with serious clinical complications when used in the pelvic floor for repair of stress urinary incontinence or support of pelvic organ prolapse. While manufacturers claim that the material is inert and non-degradable, there is a growing body of evidence that asserts PP fibres are subject to oxidative damage and indeed explanted material from patients suffering with clinical complications has shown some evidence of fibre cracking and oxidation. It has been proposed that a pathological cellular response to the surgical mesh contributes to the medical complications; however, the mechanisms that trigger the specific host response against the material are not well understood. Specifically, this study was constructed to investigate the mechano-chemical effects of oxidation and dynamic distension on polypropylene surgical mesh. To do this we used a novel advanced spectroscopical characterisation technique, secondary electron hyperspectral imaging (SEHI), which is based on the collection of secondary electron emission spectra in a scanning electron microscope (SEM) to reveal mechanical-chemical reactions within PP meshes.

Identifiers

PMID35494782
PMCPMC9042683
OpenAlexW3211072997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.