Evidence map›Paper›PMID 35494751›Full record

ArticleRSC advances2021

Understanding the metal free alginate gelation process.

Ornella Ursini, Roberta Angelini, Silvia Franco, Barbara Cortese

Abstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ornella UrsiniNanotechnology Institute -National Research Council (CNR-NANOTEC), C/o Sapienza University of Rome Piazzale A. Moro 2 00185 Rome Italy ornella.ursini@cnr.it.ORCID https://orcid.org/0000-0002-4544-3871
Roberta AngeliniInstitute for Complex Systems, National Research Council (CNR-ISC), C/o Sapienza University of Rome Piazzale A. Moro 2 00185 Rome Italy.
Silvia FrancoInstitute for Complex Systems, National Research Council (CNR-ISC), C/o Sapienza University of Rome Piazzale A. Moro 2 00185 Rome Italy.
Barbara CorteseNanotechnology Institute -National Research Council (CNR-NANOTEC), C/o Sapienza University of Rome Piazzale A. Moro 2 00185 Rome Italy ornella.ursini@cnr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alginate is a natural polysaccharide that has been recently gaining increasing attention as a biomaterial in the field of tissue engineering due to its favourable biocompatibility and gelation properties. Alginate hydrogels are commonly made by ionic crosslinking in the presence of divalent cations. Only a few studies have attempted to prepare alginate hydrogels without the presence of metal cations. Here the formation of metal free alginate hydrogels in the presence of the amino-acid glutamine is investigated. The transition from sol to gel is monitored by rheological measurements in the viscoelastic regime that reveal how the charged or neutral form of glutamine induces deep differences in the gelling ability. In particular, we show that the storage,

Identifiers

PMID35494751
PMCPMC9042680

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.