Evidence map›Paper›PMID 35494312›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2022

Epidemiological and Clinical Characteristics of Hospitalized Pediatric Patients with SARS-CoV-2 Infection in Mexico City, Mexico.

Gustavo Esteban Lugo-Zamudio, Antonio Aguilar-Rojas, Martín Uriel Vázquez-Medina, Antonio Gutiérrez-Ramírez, Ma Cristina Upton-Alvarado, Patricia Espinoza-Rivas, Gustavo Lagunas-Torres, María Isabel Rojo-Gutiérrez, Gabriela Ibáñez-Cervantes, Cruz Vargas-De-León

Open access · goldAbstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Gustavo Esteban Lugo-ZamudioDirección General, Hospital Juárez de México, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0002-3224-3571
Antonio Aguilar-RojasUnidad de Vigilancia Epidemiológica Hospitalaria, Hospital Juárez de México, Ciudad de México, Mexico.
Martín Uriel Vázquez-MedinaHospital Universitario de Puebla, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico.ORCID https://orcid.org/0000-0003-0837-7235
Antonio Gutiérrez-RamírezDivisión de Gineco-Pediatría, Hospital Juárez de México, Ciudad de México, Mexico.
Ma Cristina Upton-AlvaradoDivisión de Atención Al Usuario, Hospital Juárez de México, Ciudad de México, Mexico.
Patricia Espinoza-RivasDivisión de Gineco-Pediatría, Hospital Juárez de México, Ciudad de México, Mexico.
Gustavo Lagunas-TorresDivisión de Gineco-Pediatría, Hospital Juárez de México, Ciudad de México, Mexico.
María Isabel Rojo-GutiérrezDirección Médica, Hospital Juárez de México, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0003-4562-4477
Gabriela Ibáñez-CervantesDivisión de Investigación, Hospital Juárez de México, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0002-7969-0942
Cruz Vargas-De-LeónDivisión de Investigación, Hospital Juárez de México, Ciudad de México, Mexico.ORCID https://orcid.org/0000-0001-9428-3619
Hospital Juárez de México · MXBenemérita Universidad Autónoma de Puebla · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Evidence from across the world suggests that the pediatric population shows different clinical manifestations and has a lower risk of severe presentation of SARS-CoV-2 infection compared to adults. However, Mexico has one of the highest mortality rates in the pediatric population due to SARS-CoV-2 infection. Therefore, our objective was to explore the epidemiological and clinical characteristics associated with a positive confirmatory test in the Mexican pediatric population admitted to a tertiary care hospital in Mexico City. Methods: Clinical, imaging and laboratory data were retrospectively collected from 121 children hospitalized during the period from March 4 Results: Of the 121 children, 36 had laboratory-confirmed SARS-CoV-2 infection. The main risk for SARS-CoV-2-associated pediatric hospitalization was contact with a family member with SARS-CoV-2. It was also found that fever and fatigue were statistically significantly associated with a positive SARS-CoV-2 test in multivariate models. Clinical and laboratory data in this Mexican hospitalized pediatric cohort differ from other reports worldwide; the mortality rate (1.6%) of the population studied was higher than that seen in reports from other countries. Conclusion: Our study found that fever and fatigue at hospital presentation as well as an antecedent exposure to a family member with SARS-CoV-2 infection were important risk factors for SARS-CoV-2 positivity in children at hospital admission.

Identifiers

PMID35494312
PMCPMC9039778
OpenAlexW4224861568

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.