Evidence map›Paper›PMID 35494213›Full record

ArticleThe Lancet regional health. Europe2022

The association between common urogenital infections and cervical neoplasia - A nationwide cohort study of over four million women (2002-2018).

Filip Jansåker, Xinjun Li, Jenny Dahl Knudsen, Niels Frimodt-Møller, Christer Borgfeldt, Kristina Sundquist

Open access · goldAbstract read
In one paragraph

Article in The Lancet regional health. Europe, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Filip JansåkerCenter for Primary Health Care Research, Clinical Research Centre (CRC), Department of Clinical Sciences Malmö, Lund University, Skåne University Hospital, Jan Waldenströms gata 35, Malmö 205 02, Sweden.
Xinjun LiCenter for Primary Health Care Research, Clinical Research Centre (CRC), Department of Clinical Sciences Malmö, Lund University, Skåne University Hospital, Jan Waldenströms gata 35, Malmö 205 02, Sweden.
Jenny Dahl KnudsenDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark.
Niels Frimodt-MøllerDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark.
Christer BorgfeldtDepartment of Obstetrics and Gynaecology, Department of Clinical Sciences Lund, Skåne University Hospital, Lund University, Sweden.
Kristina SundquistCenter for Primary Health Care Research, Clinical Research Centre (CRC), Department of Clinical Sciences Malmö, Lund University, Skåne University Hospital, Jan Waldenströms gata 35, Malmö 205 02, Sweden.
Lund University · SERigshospitalet · DKShimane University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cervical cancer is a major cause of mortality and morbidity in women worldwide. This study aimed to estimate the association between common urogenital infections and cervical neoplasia. Methods: A multi-register national cohort study of 4,120,557 women aged ≥15 years (2002-2018) was conducted. The outcomes were cervical cancer and carcinoma Findings: In 39·0 million person-years of follow-up, the incidence rate for cervical cancer was 1·2 (95% CI 1·1-1·2) per 10,000 person-years and the figure for cervical carcinoma Interpretation: In this large nationwide cohort of women, medically attended common urogenital infections were independently associated with cervical neoplasia, but cystitis was not temporally associated with cervical neoplasia. These findings could be used to increase focus on preventive measures, HPV-vaccination programmes, HPV-analyses- and cervical cancer screening, especially in women suffering from vaginosis. Future studies on the causal mechanism are warranted before generalized public health recommendations can be made. Funding: Region Skåne, Tore Nilsons Stiftelse, and Swedish Society of Medicine.

Indexed as

Bacterial vaginosisCervical cancerCystitisSociodemographic factorsUrogenital infectionsVaginal infections

Identifiers

PMID35494213
PMCPMC9039866
OpenAlexW4224289093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.