Evidence map›Paper›PMID 35493910›Full record

ArticleRSC advances2020

Monte Carlo simulations using PELE to identify a protein-protein inhibitor binding site and pose.

Lucía Díaz, Daniel Soler, Gary Tresadern, Christophe Buyck, Laura Perez-Benito, Suwipa Saen-Oon, Victor Guallar, Robert Soliva

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. EngineeringiScience · 2026
    Article
  2. Article
  3. Selective inhibitors of the PSEN1-gamma-secretase complex.The Journal of biological chemistry · 2023
    Article
  4. Recent PELE Developments and Applications in Drug Discovery Campaigns.International journal of molecular sciences · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 4 countries.

Lucía DíazNostrum Biodiscovery Jordi Girona 29, Nexus II D128 08034 Barcelona Spain rsoliva@nostrumbiodiscovery.com.ORCID https://orcid.org/0000-0001-8850-2571
Daniel SolerNostrum Biodiscovery Jordi Girona 29, Nexus II D128 08034 Barcelona Spain rsoliva@nostrumbiodiscovery.com.ORCID https://orcid.org/0000-0003-3274-2482
Gary TresadernComputational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V. Turnhoutseweg 30, B-2340 Beerse Belgium gtresade@its.jnj.com.ORCID https://orcid.org/0000-0002-4801-1644
Christophe BuyckComputational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V. Turnhoutseweg 30, B-2340 Beerse Belgium gtresade@its.jnj.com.ORCID https://orcid.org/0000-0002-5711-1161
Laura Perez-BenitoComputational Chemistry, Janssen Research & Development, Janssen Pharmaceutica N. V. Turnhoutseweg 30, B-2340 Beerse Belgium gtresade@its.jnj.com.ORCID https://orcid.org/0000-0001-9607-9048
Suwipa Saen-OonNostrum Biodiscovery Jordi Girona 29, Nexus II D128 08034 Barcelona Spain rsoliva@nostrumbiodiscovery.com.ORCID https://orcid.org/0000-0002-4101-245X
Victor GuallarBarcelona Supercomputing Center, Join IRB-BSC Program in Computational Biology Spain.ORCID https://orcid.org/0000-0002-4580-1114
Robert SolivaNostrum Biodiscovery Jordi Girona 29, Nexus II D128 08034 Barcelona Spain rsoliva@nostrumbiodiscovery.com.ORCID https://orcid.org/0000-0003-0628-4342
Janssen (Belgium) · BEInstitució Catalana de Recerca i Estudis Avançats · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID35493910
PMCPMC9049779
OpenAlexW3006195452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.