Evidence map›Paper›PMID 35493905›Full record

ArticleRSC advances2020

Sustained delivery of PlGF-2

Zekang Xiong, Wei Cui, Tingfang Sun, Yu Teng, Yanzhen Qu, Liang Yang, Jinge Zhou, Kaifang Chen, Sheng Yao, Zengwu Shao and 1 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Bioactive materials · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zekang XiongDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.ORCID https://orcid.org/0000-0002-2597-4632
Wei CuiDepartment of Orthopedics, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430000 People's Republic of China.
Tingfang SunDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Yu TengDepartment of Orthopedics, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430014 People's Republic of China.
Yanzhen QuDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Liang YangDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Jinge ZhouDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Kaifang ChenDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Sheng YaoDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Zengwu ShaoDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Xiaodong GuoDepartment of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 1277 Jiefang Avenue Wuhan 430022 People's Republic of China Xiaodongguo@hust.edu.cn +86 15327216660.
Union Hospital · CNCentral Hospital of Wuhan · CNWuhan Puai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone morphogenetic protein 2 (BMP-2) is one of the most important factors for bone tissue formation. However, its use over the past decade has been associated with numerous side effects. This is due to the fact that recombinant human (rh) BMP-2 has several biological functions, as well as that non-physiological high dosages were commonly administered. In this study, we synthesized a novel BMP-2-related peptide (designated P28) and fused a mutant domain in placenta growth factor-2 (PlGF-2

Identifiers

PMID35493905
PMCPMC9049782
OpenAlexW3006893700

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.