Evidence map›Paper›PMID 35493862›Full record

ArticleRSC advances2020

3D-QSAR, molecular docking, and molecular dynamics simulation study of thieno[3,2-

Yongtao Xu, Zihao He, Hongyi Liu, Yifan Chen, Yunlong Gao, Songjie Zhang, Meiting Wang, Xiaoyuan Lu, Chang Wang, Zongya Zhao and 4 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  3. Review
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  8. RSC advances · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yongtao XuSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.ORCID https://orcid.org/0000-0002-7744-7391
Zihao HeSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Hongyi LiuSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Yifan ChenSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Yunlong GaoSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Songjie ZhangSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Meiting WangSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Xiaoyuan LuSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Chang WangSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Zongya ZhaoSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Yan LiuSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Junqiang ZhaoSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Yi YuSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Min YangSchool of Biomedical Engineering, Xinxiang Medical University Xinxiang Henan 453003 China yxu@xxmu.edu.cn yangmin@xxmu.edu.cn.
Xinxiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histone Lysine Specific Demethylase 1 (LSD1) is overexpressed in many cancers and becomes a new target for anticancer drugs. In recent years, small molecule inhibitors with various structures targeting LSD1 have been reported. Here we report the binding interaction modes of a series of thieno[3,2-

Identifiers

PMID35493862
PMCPMC9049714
OpenAlexW2969983421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.