Evidence map›Paper›PMID 35493824›Full record

ArticleFrontiers in neurology2022

Non-Invasive Neuromodulation in the Rehabilitation of Pisa Syndrome in Parkinson's Disease: A Randomized Controlled Trial.

Roberto De Icco, Alessia Putortì, Marta Allena, Micol Avenali, Carlotta Dagna, Daniele Martinelli, Silvano Cristina, Valentina Grillo, Mauro Fresia, Vito Bitetto and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Clinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Roberto De IccoMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Alessia PutortìMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Marta AllenaMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Micol AvenaliMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Carlotta DagnaMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Daniele MartinelliMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Silvano CristinaMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Valentina GrilloMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Mauro FresiaMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Vito BitettoMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Giuseppe CosentinoDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Francesca ValentinoParkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy.
Enrico AlfonsiClinical Neurophysiology Unit, IRCCS Mondino Foundation, Pavia, Italy.
Giorgio SandriniMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Antonio PisaniMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
Cristina TassorelliMovement Analysis Research Unit, IRCCS Mondino Foundation, Pavia, Italy.
University of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pisa syndrome (PS) is a frequent postural complication of Parkinson's disease (PD). PS poorly responds to anti-parkinsonian drugs and the improvement achieved with neurorehabilitation tends to fade in 6 months or less. Transcranial direct current stimulation (t-DCS) is a non-invasive neuromodulation technique that showed promising results in improving specific symptoms in different movement disorders. Objectives: This study aimed to evaluate the role of bi-hemispheric t-DCS as an add-on to a standardized hospital rehabilitation program in the management of PS in PD. Methods: This study included 28 patients with PD and PS (21 men, aged 72.9 ± 5.1 years) who underwent a 4-week intensive neurorehabilitation treatment and were randomized to receive: i) t-DCS (t-DCS group, Results: When compared to the sham group, the t-DCS group achieved a more pronounced improvement in several variables: overall posture ( Conclusions: Our data support the use of neuromodulation with t-DCS as an add-on to neurorehabilitation for the treatment of patients affected by PS in PD.

Indexed as

lateral trunk inclinationmovement analysismovement disordersneurorehabilitationparkinsonismtranscranial direct current stimulation (tDCS)

Identifiers

PMID35493824
PMCPMC9046718
OpenAlexW4223896560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.