Evidence map›Paper›PMID 35493695›Full record

ArticleACS sustainable chemistry & engineering2022

Family 1 Glycosyltransferase UGT706F8 from

Gonzalo N Bidart, Natalia Putkaradze, Folmer Fredslund, Christian Kjeldsen, Ander Garralda Ruiz, Jens Ø Duus, David Teze, Ditte H Welner

Open access · hybridAbstract read
In one paragraph

Article in ACS sustainable chemistry & engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Structure-function and engineering of plant UDP-glycosyltransferase.Computational and structural biotechnology journal · 2023
    Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gonzalo N BidartThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.
Natalia PutkaradzeThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.
Folmer FredslundThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.ORCID https://orcid.org/0000-0003-0881-1927
Christian KjeldsenDTU Chemistry, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.ORCID https://orcid.org/0000-0002-0976-6622
Ander Garralda RuizThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.
Jens Ø DuusDTU Chemistry, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.ORCID https://orcid.org/0000-0003-3625-1250
David TezeThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.ORCID https://orcid.org/0000-0002-6865-6108
Ditte H WelnerThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.ORCID https://orcid.org/0000-0001-9297-4133
Novo Nordisk Foundation · DKTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regioselective glycosylation is a chemical challenge, leading to multistep syntheses with protecting group manipulations, ultimately resulting in poor atom economy and compromised sustainability. Enzymes allow eco-friendly and regioselective bond formation with fully deprotected substrates in a single reaction. For the selective glucosylation of silibinin, a pharmaceutical challenged with low solubility, enzyme engineering has previously been employed, but the resulting yields and

Identifiers

PMID35493695
PMCPMC9045260
OpenAlexW4223540549

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.