ArticleRSC advances2020
Synthesis of polyacrylonitrile nanoflowers and their controlled pH-sensitive drug release behavior.
Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Nude and Modified Electrospun Nanofibers, Application to Air Purification.Nanomaterials (Basel, Switzerland) · 2023Review
- Polyaniline Nanoskein: Synthetic Method, Characterization, and Redox Sensing.Nanoscale research letters · 2020Article
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Authors and funding
6 authors.
Funding
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Abstract
A novel controlled drug release system based on pH sensitive polyacrylonitrile (PAN) nanoflowers in different kinds of solvents was successfully prepared with azobisisobutyronitrile (AIBN) as the initiator and without any emulsifier or stabilizer by a one step static polymerization method. The composition and structure of the PAN nanoflowers were analyzed by FTIR, XRD, SEM, TEM, and laser particle size analysis. The polymer particles consisted of a number of lamellae, with a sheet thickness of about 10 nm, and were similar to the shape of flowers with a particle diameter of about 350 nm. The mechanism of the polymerization reaction and the formation were studied. Moreover, the effects of monomer ratio, initiator concentration, reaction time, dispersion medium and co-monomer on the morphology and particle size of the nanoflowers were also discussed. A relatively large specific surface area was formed during the formation of the nanoflowers, which favored drug adsorption. The results of the
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