Evidence map›Paper›PMID 35493523›Full record

ArticleFrontiers in immunology2022

Acidic Microenvironments Found in Cutaneous

Linus Frick, Linda Hinterland, Kathrin Renner, Marion Vogl, Nathalie Babl, Simon Heckscher, Anna Weigert, Susanne Weiß, Joachim Gläsner, Raffaela Berger and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Linus FrickInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
Linda HinterlandInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
Kathrin RennerDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.
Marion VoglInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
Nathalie BablDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.
Simon HeckscherInstitute of Functional Genomics, University of Regensburg, Regensburg, Germany.
Anna WeigertInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
Susanne WeißInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
Joachim GläsnerInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
Raffaela BergerInstitute of Functional Genomics, University of Regensburg, Regensburg, Germany.
Peter J OefnerInstitute of Functional Genomics, University of Regensburg, Regensburg, Germany.
Katja DettmerInstitute of Functional Genomics, University of Regensburg, Regensburg, Germany.
Marina KreutzDepartment of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany.
Valentin SchatzInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
Jonathan JantschInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.
University of Regensburg · DEUniversity Hospital Regensburg · DELeibniz Institute for Immunotherapy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Local tissue acidosis affects anti-tumor immunity. In contrast, data on tissue pH levels in infected tissues and their impact on antimicrobial activity is sparse. In this study, we assessed the pH levels in cutaneous

Indexed as

Anti-Infective AgentsLeishmania majorAntiparasitic AgentsMacrophagesNitric OxideAnti-Infective AgentsAntiparasitic AgentsNitric OxideLeishmaniamacrophagesNONOS2pH

Identifiers

PMID35493523
PMCPMC9047701
OpenAlexW4285685146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.