Evidence map›Paper›PMID 35493484›Full record

ReviewFrontiers in immunology2022

Aspects of the Complement System in New Era of Xenotransplantation.

Shuji Miyagawa, Akira Maeda, Chiyoshi Toyama, Shuhei Kogata, Chizu Okamatsu, Riho Yamamoto, Kazunori Masahata, Masafumi Kamiyama, Hiroshi Eguchi, Masahito Watanabe and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Complement activation in kidney transplantation.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Review
  3. Review
  4. Review
  5. Current status and prospects of genetically modified porcine-to-human cardiac xenotransplantation.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Review
  6. [Research and application progress for liver xenotransplantation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Milestones on the path to clinical pig organ xenotransplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Shuji MiyagawaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Akira MaedaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Chiyoshi ToyamaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Shuhei KogataDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Chizu OkamatsuDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Riho YamamotoDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Kazunori MasahataDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Masafumi KamiyamaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Hiroshi EguchiDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Masahito WatanabeInternational Institute for Bio-Resource Research, Meiji University, Kanagawa, Japan.
Hiroshi NagashimaInternational Institute for Bio-Resource Research, Meiji University, Kanagawa, Japan.
Masahito IkawaResearch Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Katsuyoshi MatsunamiDepartment of Pharmacognosy, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Hiroomi OkuyamaDepartment of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Osaka University · JPMeiji University · JPHiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After producing triple (Gal, H-D and Sd

Indexed as

Complement System ProteinsGraft RejectionAnimalsAntigens, HeterophileComplement ActivationHumansSwineTransplantation, HeterologousAntigens, HeterophileComplement System Proteinscomplement-immunological termscomplement receptorcomplement regulatory proteingene-modified pigslocally produced complementnon-Gal antigens

Identifiers

PMID35493484
PMCPMC9046582
OpenAlexW4224044353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.