Evidence map›Paper›PMID 35493375›Full record

ArticleFrontiers in public health2022

A Transfer Learning Method for Detecting Alzheimer's Disease Based on Speech and Natural Language Processing.

Ning Liu, Kexue Luo, Zhenming Yuan, Yan Chen

Abstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ning LiuSchool of Public Health, Hangzhou Normal University, Hangzhou, China.
Kexue LuoTongde Hospital of Zhejiang Province Geriatrics, Hangzhou, China.
Zhenming YuanSchool of Information Science and Technology, Hangzhou Normal University, Hangzhou, China.
Yan ChenInternational Unresponsive Wakefulness Syndrome and Consciousness Science Institute, Hangzhou Normal University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease that is difficult to be detected using convenient and reliable methods. The language change in patients with AD is an important signal of their cognitive status, which potentially helps in early diagnosis. In this study, we developed a transfer learning model based on speech and natural language processing (NLP) technology for the early diagnosis of AD. The lack of large datasets limits the use of complex neural network models without feature engineering, while transfer learning can effectively solve this problem. The transfer learning model is firstly pre-trained on large text datasets to get the pre-trained language model, and then, based on such a model, an AD classification model is performed on small training sets. Concretely, a distilled bidirectional encoder representation (distilBert) embedding, combined with a logistic regression classifier, is used to distinguish AD from normal controls. The model experiment was evaluated on Alzheimer's dementia recognition through spontaneous speech datasets in 2020, including the balanced 78 healthy controls (HC) and 78 patients with AD. The accuracy of the proposed model is 0.88, which is almost equivalent to the champion score in the challenge and a considerable improvement over the baseline of 75% established by organizers of the challenge. As a result, the transfer learning method in this study improves AD prediction, which does not only reduces the need for feature engineering but also addresses the lack of sufficiently large datasets.

Indexed as

Alzheimer DiseaseNeurodegenerative DiseasesHumansMachine LearningNatural Language ProcessingSpeechAlzheimer's diseaseBERTmachine learningnatural language processingtransfer learning

Identifiers

PMID35493375
PMCPMC9043451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.