Evidence map›Paper›PMID 35493315›Full record

ArticleJournal of traditional and complementary medicine2022

Anti-rheumatoid activity of a hexane-insoluble fraction from

Asih Triastuti, Dimas Adhi Pradana, Didit Erwin Saputra, Namira Lianika, Hilmy Ramadhan Wicaksono, Thessy Dewi Anisari, Sitarina Widyarini

Open access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Anti-Arthritis Effect of Ethanol Extract of Sacha Inchi (Tropical life sciences research · 2023
    Article
  6. Research in pharmaceutical sciences · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Asih TriastutiDepartment of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia.
Dimas Adhi PradanaDepartment of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia.
Didit Erwin SaputraDepartment of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia.
Namira LianikaDepartment of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia.
Hilmy Ramadhan WicaksonoDepartment of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia.
Thessy Dewi AnisariDepartment of Pharmacy, Universitas Islam Indonesia, Yogyakarta, Indonesia.
Sitarina WidyariniDepartment of Pathology Faculty of Veterinary Medicine Universitas Gadjah Mada, Indonesia.
Islamic University of Indonesia · IDUniversitas Gadjah Mada · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Experimental procedure: The anti-arthritic properties of an n-hexane-insoluble fraction of dichloromethane extracts of Results: The IPM extract at doses of 280 and 420 mg/kg BW and diclofenac inhibited paw oedema by 15.70 %, 15.94 % and 19.71 % respectively. IPM also reduced the incidence of arthritis and arthritic index. Unlike untreated rats, animals treated with IPM showed a significant decrease in the number of neutrophils and decreased expression of TNF-α and Interleukin-6. Histopathological examination showed a reduction in the number of inflammatory cells and hyperplasia of the synovium after IPM treatment. Conclusion: This study showed that

Indexed as

ArthritisCytokinesHistopathologyPaw oedema

Identifiers

PMID35493315
PMCPMC9039107
OpenAlexW3184377946

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.