Evidence map›Paper›PMID 35493285›Full record

ArticleInternational journal of rheumatology2022

Polymorphism in STAT4 Increase the Risk of Systemic Lupus Erythematosus: An Updated Meta-Analysis.

Shancui-Zheng, Jinping-Zhang, Guoyuan-Lu, Lei Liu, Zhiyong-Deng

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Genetic association betweenFrontiers in genetics · 2025
    Article
  2. Article
  3. STAT4 gene polymorphisms in human diseases.Frontiers in immunology · 2024
    Review
  4. Association of theGenes · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shancui-ZhengDepartment of Nephrology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Jinping-ZhangInstitutions of Biology and Medical Sciences, Soochow University, Suzhou 215006, China.
Guoyuan-LuDepartment of Nephrology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.ORCID https://orcid.org/0000-0003-4945-8509
Lei LiuDepartment of Rheumatology and Clinical Immunology, The First People's Hospital of Kunshan, Suzhou 215300, China.
Zhiyong-DengDepartment of Rheumatology and Clinical Immunology, The First People's Hospital of Kunshan, Suzhou 215300, China.
Soochow University · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have reported that STAT4 rs7574865 conferred the susceptibility to systemic lupus erythematosus (SLE). In this study, a meta-analysis (including 32 comparative studies of 11384 patients and 17609 controls) was conducted to investigate the role of STAT4 polymorphism in SLE in a comprehensive way. We found that the Asian population had the highest prevalence of the T allele than any other study population at 32.2% and that STAT4 rs7574865 polymorphism was associated with SLE in the overall population (OR = 1.579, 95%CI = 1.497-1.665,

Identifiers

PMID35493285
PMCPMC9054488
OpenAlexW4224289482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.