Evidence map›Paper›PMID 35493129›Full record

ArticleOpen forum infectious diseases2022

Correlates of 90-Day Mortality Among People Who Do and Do Not Inject Drugs With Infective Endocarditis in Seattle, Washington.

Maria A Corcorran, Jenell Stewart, Kristine Lan, Ayushi Gupta, Sara N Glick, Chetan Seshadri, Kevin J Koomalsingh, Edward F Gibbons, Robert D Harrington, Shireesha Dhanireddy and 1 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Maria A CorcorranDepartment of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-4935-5166
Jenell StewartDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Kristine LanDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Ayushi GuptaDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Sara N GlickDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Chetan SeshadriDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Kevin J KoomalsinghProvidence Heart Institute, Portland, Oregon, USA.
Edward F GibbonsDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Robert D HarringtonDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Shireesha DhanireddyDepartment of Medicine, University of Washington, Seattle, Washington, USA.
H Nina KimDepartment of Medicine, University of Washington, Seattle, Washington, USA.
University of Washington · USProvidence College · USPublic Health – Seattle & King County · US

Funding

HOST DEFENSE TRAINING IN ALLERGY AND INFECTIOUS DISEASEST32AI007044 · NIAID · UNIVERSITY OF WASHINGTON · PI DAVID Neal FREDRICKS · 1985 to 2026
$14.6M
UNIVERSITY OF WASHINGTON GI TRAINING GRANTT32DK007742 · NIDDK · UNIVERSITY OF WASHINGTON · PI GRADY, WILLIAM MALLORY · 1996 to 2022
$4.7M
Understanding STI and HIV prevention adherence among Kenyan womenK23MH124466 · NIMH · UNIVERSITY OF WASHINGTON · PI STEWART, JENELL · 2020 to 2024
$939k
NIAID NIH HHS T32 AI007044NIDDK NIH HHS T32 DK007742NIMH NIH HHS K23 MH124466
6 · The paper itself

Abstract

Background: Infective endocarditis (IE) remains highly morbid, but few studies have evaluated factors associated with IE mortality. We examined correlates of 90-day mortality among people who inject drugs (PWID) and people who do not inject drugs (non-PWID). Methods: We queried the electronic medical record for cases of IE among adults ≥18 years of age at 2 academic medical centers in Seattle, Washington, from 1 January 2014 to 31 July 2019. Cases were reviewed to confirm a diagnosis of IE and drug use status. Deaths were confirmed through the Washington State death index. Descriptive statistics were used to characterize IE in PWID and non-PWID. Kaplan-Meier log-rank tests and Cox proportional hazard models were used to assess correlates of 90-day mortality. Results: We identified 507 patients with IE, 213 (42%) of whom were PWID. Sixteen percent of patients died within 90 days of admission, including 14% of PWID and 17% of non-PWID ( Conclusions: Overall 90-day mortality did not differ between PWID and non-PWID with IE, although PWID experienced a higher risk of death within 14 days of admission. These findings suggest that early IE diagnosis and treatment among PWID is critical to improving outcomes.

Indexed as

infective endocarditismortalitypeople who inject drugsPWID

Identifiers

PMID35493129
PMCPMC9045945
OpenAlexW4220997589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.