Evidence map›Paper›PMID 35493115›Full record

ArticleOpen forum infectious diseases2022

Implementation of IV Push Antibiotics for Outpatients During a National Fluid Shortage Following Hurricane Maria.

Kruti J Yagnik, L Steven Brown, Hala A Saad, Kristin Alvarez, Norman Mang, Cylaina E Bird, Fred Cerise, Kavita P Bhavan

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Association Between a Shortage of Normal Saline and In-Hospital Outcomes Among Individuals With Febrile Neutropenia.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2026
    Article
  5. Article
  6. Article
  7. Real-world evaluation of ceftriaxone-related safety events: a stewardship call to action.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. A Bundle of the Top 10 OPAT Publications in 2022.Open forum infectious diseases · 2023
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kruti J YagnikDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID https://orcid.org/0000-0001-6494-2142
L Steven BrownOffice of Research Administration, Parkland Health, Dallas, Texas, USA.
Hala A SaadDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kristin AlvarezCenter of Innovation and Value at Parkland, Parkland Health, Dallas, Texas, USA.
Norman MangPharmacy Department, Parkland Health, Dallas, Texas, USA.
Cylaina E BirdDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Fred CeriseOffice of Research Administration, Parkland Health, Dallas, Texas, USA.
Kavita P BhavanDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Parkland Health & Hospital System · USThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prior to the introduction of intravenous (IV) drip infusion, most IV drugs were delivered in a syringe bolus push. However, intravenous drip infusions subsequently became the standard of care. Puerto Rico is the largest supplier of IV fluid bags and in the aftermath of Hurricane Maria, there was a nationwide fluid bag shortage. This shortage required stewardship measures to maintain the operation of the self-administered outpatient parenteral antimicrobial therapy (OPAT) program at Parkland Health. Methods: Parkland pharmacists evaluated all self-administered antimicrobials for viability of administration as an IV syringe bolus push (IVP) instead of an IV-drip infusion. Medications deemed appropriate were transitioned to IVP. The hospital EMR was used to identify patients discharged to the OPAT clinic using all methods of parenteral drug delivery. Data was collected for patient demographics, patient satisfaction, and clinical outcomes. Finally cost of care was calculated for IVP and IV drip administration. Results: One-hundred and thirteen self-administered IVP and 102 self-administered IV drip treatment courses were identified during the study period. Individuals using IVP had a statistically significant decrease in hospital length of stay. Patient satisfaction was greater with IVP and IVP saved 504 liters of normal saline resulting in a savings of $43,652 over 6 months. The 30-day readmission rate and mortality were similar. Conclusion: The abrupt IV fluid shortage following a natural disaster led to implementation of a high value care model that improved efficiency, reduced costs, and did not affect safety or efficacy.

Indexed as

cost-savingsfluid shortagehigh-value careHurricane MariaIV antibioticsOPAT

Identifiers

PMID35493115
PMCPMC9045948
OpenAlexW4225326860

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.