Evidence map›Paper›PMID 35492907›Full record

ArticleRSC advances2020

Enzymatic approach to cascade synthesis of bis(indolyl)methanes in pure water.

Yajie Fu, Zeping Lu, Ke Fang, Xinyi He, Huajin Xu, Yi Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yajie FuState Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 210009 China huyi@njtech.edu.cn dg1224097@smail.nju.edu.cn.
Zeping LuState Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 210009 China huyi@njtech.edu.cn dg1224097@smail.nju.edu.cn.
Ke FangState Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 210009 China huyi@njtech.edu.cn dg1224097@smail.nju.edu.cn.
Xinyi HeState Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 210009 China huyi@njtech.edu.cn dg1224097@smail.nju.edu.cn.
Huajin XuState Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 210009 China huyi@njtech.edu.cn dg1224097@smail.nju.edu.cn.
Yi HuState Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 210009 China huyi@njtech.edu.cn dg1224097@smail.nju.edu.cn.ORCID https://orcid.org/0000-0001-7736-4433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A mild, efficient, and green protocol was developed for the synthesis of bis(indolyl)methanes catalyzed by lipase TLIM through the cascade reactions of indole with aldehydes in pure water. This methodology offers many superiorities such as excellent yields, wide substrate range, simple procedure, reusable and minimal amount of catalyst, and the ability to be scaled up.

Identifiers

PMID35492907
PMCPMC9050360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.