Evidence map›Paper›PMID 35492793›Full record

ArticleRSC advances2021

One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry.

Takashi Nakakoji, Hirofumi Sato, Daisuke Ono, Hiroyuki Miyake, Eiko Mieda, Satoshi Shinoda, Hiroshi Tsukube, Hideya Kawasaki, Ryuichi Arakawa, Motohiro Shizuma

Abstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. D-Amino acid analysis in solution using the photochemical properties of protonated adenosine.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takashi NakakojiDepartment of Chemistry, Graduate School of Science, Osaka City University Sugimoto, Sumiyoshi-ku Osaka 558-8585 Japan miyake@sci.osaka-cu.ac.jp.
Hirofumi SatoOsaka Research Institute of Industrial Science and Technology Morinomiya, Joto-ku Osaka 536-8553 Japan shizuma@omtri.or.jp.
Daisuke OnoOsaka Research Institute of Industrial Science and Technology Morinomiya, Joto-ku Osaka 536-8553 Japan shizuma@omtri.or.jp.
Hiroyuki MiyakeDepartment of Chemistry, Graduate School of Science, Osaka City University Sugimoto, Sumiyoshi-ku Osaka 558-8585 Japan miyake@sci.osaka-cu.ac.jp.
Eiko MiedaDepartment of Chemistry, Graduate School of Science, Osaka City University Sugimoto, Sumiyoshi-ku Osaka 558-8585 Japan miyake@sci.osaka-cu.ac.jp.
Satoshi ShinodaDepartment of Chemistry, Graduate School of Science, Osaka City University Sugimoto, Sumiyoshi-ku Osaka 558-8585 Japan miyake@sci.osaka-cu.ac.jp.ORCID https://orcid.org/0000-0001-7735-8156
Hiroshi TsukubeDepartment of Chemistry, Graduate School of Science, Osaka City University Sugimoto, Sumiyoshi-ku Osaka 558-8585 Japan miyake@sci.osaka-cu.ac.jp.
Hideya KawasakiDepartment of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University Yamate-cho, Suita Osaka 564-8680 Japan.ORCID https://orcid.org/0000-0003-2713-2057
Ryuichi ArakawaDepartment of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University Yamate-cho, Suita Osaka 564-8680 Japan.
Motohiro ShizumaOsaka Research Institute of Industrial Science and Technology Morinomiya, Joto-ku Osaka 536-8553 Japan shizuma@omtri.or.jp.ORCID https://orcid.org/0000-0002-8682-7660

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An electrospray ionization mass spectrometric method for the simultaneous analysis of the enantiomeric excess of free amino acids, without chromatographic separation, was demonstrated using a quasi-racemic mixture of deuterium-labelled and unlabelled chiral copper(ii) complexes. This convenient method enables the simultaneous high-sensitivity determination of the enantiomeric excess of 12 amino acids.

Identifiers

PMID35492793
PMCPMC9043479

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.