Evidence map›Paper›PMID 35492790›Full record

ArticleRSC advances2021

A comparison of acyl-moieties for noncovalent functionalization of PLGA and PEG-PLGA nanoparticles with a cell-penetrating peptide.

Omar Paulino da Silva Filho, Muhanad Ali, Rike Nabbefeld, Daniel Primavessy, Petra H Bovee-Geurts, Silko Grimm, Andreas Kirchner, Karl-Heinz Wiesmüller, Marc Schneider, X Frank Walboomers and 1 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Omar Paulino da Silva FilhoDepartment of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center Geert Grooteplein 28 6525 GA Nijmegen The Netherlands roland.brock@radboudumc.nl.ORCID https://orcid.org/0000-0001-5036-170X
Muhanad AliDepartment of Odontology and Biomaterials, Radboud University Medical Center Nijmegen The Netherlands.
Rike NabbefeldDepartment of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center Geert Grooteplein 28 6525 GA Nijmegen The Netherlands roland.brock@radboudumc.nl.
Daniel PrimavessyDepartment of Biopharmacy and Pharmaceutic Technology, Saarland University 66123 Saarbrücken Germany.ORCID https://orcid.org/0000-0002-3569-5231
Petra H Bovee-GeurtsDepartment of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center Geert Grooteplein 28 6525 GA Nijmegen The Netherlands roland.brock@radboudumc.nl.
Silko GrimmEvonik Industries, Health Care, Formulation and Polymers Kirschenallee 64293 Darmstadt Germany.
Andreas KirchnerDepartment of Biopharmacy and Pharmaceutic Technology, Saarland University 66123 Saarbrücken Germany.
Karl-Heinz WiesmüllerEMC Microcollections GmbH Sindelfinger Str. 3 72070 Tübingen Germany.ORCID https://orcid.org/0000-0002-6532-2399
Marc SchneiderDepartment of Biopharmacy and Pharmaceutic Technology, Saarland University 66123 Saarbrücken Germany.ORCID https://orcid.org/0000-0002-9260-7357
X Frank WalboomersDepartment of Odontology and Biomaterials, Radboud University Medical Center Nijmegen The Netherlands.
Roland BrockDepartment of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center Geert Grooteplein 28 6525 GA Nijmegen The Netherlands roland.brock@radboudumc.nl.ORCID https://orcid.org/0000-0003-1395-6127
Radboud University Nijmegen · NLSaarland University · DEEMC Microcollections (Germany) · DEEvonik (Germany) · DEMinistry of Education · BRPhilipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient intracellular drug delivery in nanomedicine strongly depends on ways to induce cellular uptake. Conjugation of nanoparticles (NPs) with cell-penetrating peptides (CPPs) is a known means to induce uptake

Identifiers

PMID35492790
PMCPMC9043423
OpenAlexW3213655767

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.