Evidence map›Paper›PMID 35492709›Full record

ArticleFrontiers in psychiatry2022

Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder.

Nicolas A Nunez, Brandon J Coombes, Francisco Romo-Nava, David J Bond, Jennifer Vande Voort, Paul E Croarkin, Nicole Leibman, Manuel Gardea Resendez, Marin Veldic, Hannah Betcher and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 3 countries.

Nicolas A NunezDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Brandon J CoombesDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.
Francisco Romo-NavaLindner Center of HOPE /University of Cincinnati, Cincinnati, OH, United States.
David J BondDepartment of Psychiatry & Behavioral Sciences, University of Minnesota Medical School, Minneapolis, MN, United States.
Jennifer Vande VoortDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Paul E CroarkinDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Nicole LeibmanDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Manuel Gardea ResendezDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Marin VeldicDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Hannah BetcherDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Balwinder SinghDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Colin ColbyDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.
Alfredo Cuellar-BarbozaDepartment of Psychiatry, Universidad Autónoma de Nuevo León, Monterrey, Mexico.
Miguel PrietoDepartment of Psychiatry, Facultad de Medicina, Universidad de los Andes, Santiago, Chile.
Katherine M MooreDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Aysegul OzerdemDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Susan L McElroyLindner Center of HOPE /University of Cincinnati, Cincinnati, OH, United States.
Mark A FryeDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Joanna M BiernackaDepartment of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic · USWinnMed · USMayo Clinic in Florida · USUniversity of Cincinnati · USUniversidad Autónoma de Nuevo León · MXUniversidad de Los Andes, Chile · CLUniversity of Minnesota Medical Center · US

Funding

The role of the circadian system in binge eating disorderK23MH120503 · NIMH · UNIVERSITY OF CINCINNATI · PI ROMO-NAVA, FRANCISCO · 2020 to 2023
$803k
NIMH NIH HHS K23 MH120503
6 · The paper itself

Abstract

Background: Bipolar disorder (BD) with co-occurring attention deficit-hyperactivity disorder (ADHD) is associated with an unfavorable course of illness. We aimed to identify potential clinical and genetic correlates of BD with and without ADHD. Methods: Among patients with BD ( Results: Compared to the non-ADHD BD group, BD+cADHD patients were younger, more often men and had a greater number of co-occurring anxiety and substance use disorders (all Conclusions: BD+cADHD was associated with a greater number of comorbidities and reduced response to mood stabilizing treatments. The higher ADHD PRS for the BD+cADHD group may reflect a greater influence of genetic factors on early presentation of ADHD symptoms.

Indexed as

ADHDbipolar disorderclinical featuresgeneticpolygenic risk score

Identifiers

PMID35492709
PMCPMC9047940
OpenAlexW4224050008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.