Evidence map›Paper›PMID 35492655›Full record

ArticleRSC advances2020

Cost-effective fabrication of photopolymer molds with multi-level microstructures for PDMS microfluidic device manufacture.

Carol M Olmos, Ana Peñaherrera, Gustavo Rosero, Karla Vizuete, Darío Ruarte, Marie Follo, Andrea Vaca, Carlos R Arroyo, Alexis Debut, Luis Cumbal and 3 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 6 countries.

Carol M OlmosUniversidad Tecnológica Nacional (UTN), Facultad Regional Haedo Haedo Buenos Aires E 1706 Argentina belerner@fiu.edu.
Ana PeñaherreraUniversidad Tecnológica Nacional (UTN), Facultad Regional Haedo Haedo Buenos Aires E 1706 Argentina belerner@fiu.edu.
Gustavo RoseroUniversidad Tecnológica Nacional (UTN), Facultad Regional Haedo Haedo Buenos Aires E 1706 Argentina belerner@fiu.edu.
Karla VizueteUniversidad de las Fuerzas Armadas ESPE, Centro de Nanociencia y Nanotecnología P. O. Box 171-5-231B Sangolqui Ecuador.
Darío RuarteDepartment of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg Germany roland.mertelsmann@uniklinik-freiburg.de.
Marie FolloDepartment of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg Germany roland.mertelsmann@uniklinik-freiburg.de.
Andrea VacaUniversidad Tecnológica Nacional (UTN), Facultad Regional Haedo Haedo Buenos Aires E 1706 Argentina belerner@fiu.edu.
Carlos R ArroyoUniversidad de las Fuerzas Armadas ESPE, Centro de Nanociencia y Nanotecnología P. O. Box 171-5-231B Sangolqui Ecuador.
Alexis DebutUniversidad de las Fuerzas Armadas ESPE, Centro de Nanociencia y Nanotecnología P. O. Box 171-5-231B Sangolqui Ecuador.
Luis CumbalUniversidad de las Fuerzas Armadas ESPE, Centro de Nanociencia y Nanotecnología P. O. Box 171-5-231B Sangolqui Ecuador.
Maximiliano S PérezUniversidad Tecnológica Nacional (UTN), Facultad Regional Haedo Haedo Buenos Aires E 1706 Argentina belerner@fiu.edu.
Betiana LernerUniversidad Tecnológica Nacional (UTN), Facultad Regional Haedo Haedo Buenos Aires E 1706 Argentina belerner@fiu.edu.
Roland MertelsmannDepartment of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg Germany roland.mertelsmann@uniklinik-freiburg.de.ORCID https://orcid.org/0000-0002-0294-0325
National Technological University · ARUniversidad de las Fuerzas Armadas ESPE · ECUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper describes a methodology of photopolymer mold fabrication with multi-level microstructures for polydimethylsiloxane (PDMS) microfluidic device manufacture. Multi-level microstructures can be performed by varying UVA exposure time and channel width. Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM) and profilometry techniques have been employed to characterize the molds. Multiple molds with multi-level microstructures can be formed in a unique piece. Overall height/depth of the structures reaches up to 677 μm and a minimum of 21 μm. The method provides several advantages such as reduction of fabrication time, multiple structures with diverse topologies, a great variety of depth and height in a single mold and low cost of fabrication. The effectiveness of multi-level microstructure fabrication was evaluated by constructing PDMS microfluidic devices for cell culture and proliferation.

Identifiers

PMID35492655
PMCPMC9048755
OpenAlexW3002703482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.