Evidence map›Paper›PMID 35492646›Full record

ArticleRSC advances2020

Inhibition of human thrombin by the constituents of licorice: inhibition kinetics and mechanistic insights through

Cheng-Cheng Shi, Tian-Ran Chen, Qi-Hua Zhang, Ling-Hua Wei, Chao Huang, Ya-Di Zhu, Hai-Bin Liu, Ya-Kun Bai, Fang-Jun Wang, Wen-Zhi Guo and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Licorice (Plants (Basel, Switzerland) · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Cheng-Cheng ShiDepartment of Pharmacology, School of Basic Medical Sciences, Zhengzhou University Zhengzhou Henan China zhanglirongzzu@126.com.
Tian-Ran ChenInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine Shanghai China geguangbo@dicp.ac.cn.
Qi-Hua ZhangCAS Key Laboratory of Receptor Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences Shanghai China.
Ling-Hua WeiHenan Key Laboratory of Digestive Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University Zhengzhou China guowz66@163.com.
Chao HuangInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine Shanghai China geguangbo@dicp.ac.cn.
Ya-Di ZhuInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine Shanghai China geguangbo@dicp.ac.cn.
Hai-Bin LiuNational Engineering Research Center for Gelatin-based Traditional Chinese Medicine, Dong-E-E-Jiao Co. Ltd. Done-E Shandong China.
Ya-Kun BaiHenan Key Laboratory of Digestive Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University Zhengzhou China guowz66@163.com.
Fang-Jun WangCAS Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences Dalian 116023 China.ORCID https://orcid.org/0000-0002-8118-7019
Wen-Zhi GuoHenan Key Laboratory of Digestive Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University Zhengzhou China guowz66@163.com.
Li-Rong ZhangDepartment of Pharmacology, School of Basic Medical Sciences, Zhengzhou University Zhengzhou Henan China zhanglirongzzu@126.com.
Guang-Bo GeInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine Shanghai China geguangbo@dicp.ac.cn.ORCID https://orcid.org/0000-0002-9670-4349
First Affiliated Hospital of Zhengzhou University · CNShanghai University of Traditional Chinese Medicine · CNDalian Institute of Chemical Physics · CNZhengzhou University · CNChinese Academy of Sciences · CNDong-A Pharmaceutical (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombin inhibition therapy is a practical strategy to reduce thrombotic and cardiovascular risks

Identifiers

PMID35492646
PMCPMC9048847
OpenAlexW3000985102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.