Evidence map›Paper›PMID 35492449›Full record

ArticleRSC advances2021

Unravelling the anticancer potential of a square planar copper complex: toward non-platinum chemotherapy.

Manzoor Ahmad Malik, Md Kausar Raza, Arif Mohammed, Mohmmad Younus Wani, Abdullah Saad Al-Bogami, Athar Adil Hashmi

Abstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manzoor Ahmad MalikBioinorganic Lab., Department of Chemistry, Jamia Millia Islamia New Delhi 110025 India manzoormalik.kash@gmail.com.
Md Kausar RazaDepartment of Inorganic and Physical Chemistry, Indian Institute of Science Bangalore 560012 India.ORCID https://orcid.org/0000-0002-9175-198X
Arif MohammedDepartment of Biology, College of Science, University of Jeddah Jeddah 21589 Saudi Arabia.
Mohmmad Younus WaniDepartment of Chemistry, College of Science, University of Jeddah Jeddah 21589 Saudi Arabia mwani@uj.edu.sa.ORCID https://orcid.org/0000-0002-1838-1337
Abdullah Saad Al-BogamiDepartment of Chemistry, College of Science, University of Jeddah Jeddah 21589 Saudi Arabia mwani@uj.edu.sa.ORCID https://orcid.org/0000-0002-8670-2729
Athar Adil HashmiBioinorganic Lab., Department of Chemistry, Jamia Millia Islamia New Delhi 110025 India manzoormalik.kash@gmail.com.ORCID https://orcid.org/0000-0002-7854-8290

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coordination compounds from simple transition metals are robust substitutes for platinum-based complexes due to their remarkable anticancer properties. In a quest to find new metal complexes that could substitute or augment the platinum based chemotherapy we synthesized three transition metal complexes C1-C3 with Cu(ii), Ni(ii), and Co(ii) as the central metal ions, respectively, and evaluated them for their anticancer activity against the human keratinocyte (HaCaT) cell line and human cervical cancer (HeLa) cell lines. These complexes showed different activity profiles with the square planar copper complex C1 being the most active with IC

Identifiers

PMID35492449
PMCPMC9044439

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.