ArticleFrontiers in medicine2022
Case Report: Pediatric Hepatic Rhabdomyosarcoma With Maximum Lifetime.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Adult liver rhabdomyosarcoma complicated with sarcomatoid carcinoma: A case report.World journal of gastrointestinal oncology · 2026Article
- Primary Liver Rhabdomyosarcoma with Burnt-out Paravertebral Disease.Indian journal of pediatrics · 2025Article
- Successful management strategy for giant primary hepatic rhabdomyosarcoma in 15-year-old male: a case report.Journal of surgical case reports · 2024Article
- Primary Esophageal Rhabdomyosarcoma: An Exceptionally Rare Cause of Pediatric Dysphagia.Case reports in gastrointestinal medicine · 2024Article
- About a Large Botryoid Rhabdomyosarcoma in a Little Girl: Management Difficulties and Literature Review.Case reports in obstetrics and gynecology · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
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Abstract
Primary intrahepatic rhabdomyosarcoma is an extremely rare malignant tumor. Here, we describe a case of embryonal rhabdomyosarcoma of the liver in a 7-year-old boy without any symptoms. Serologically, the patient showed abnormal levels of serum tumor markers and liver function. Imaging revealed a large mass in the left lobe of the liver and no lesions elsewhere. At first, the patient was misdiagnosed by percutaneous liver biopsy as having clear cell sarcoma. However, the final diagnosis was established to be hepatic embryonal rhabdomyosarcoma based on postoperative histopathology and typical immunohistochemical staining, which was positive for desmin and myogenin. For treatment, the patient received two cycles of preoperative chemotherapy, prophylactic radiotherapy, and 13 cycles of combined postoperative chemotherapy. Routine follow-ups after all treatment conducted by imaging examinations showed no sign of recurrence or metastasis over 13 months, and the patient survives more than 38 months since initial diagnosis. To our knowledge, this patient is the first with hepatic rhabdomyosarcoma to receive neoadjuvant chemotherapy (preoperative chemotherapy) combined with relative comprehensive treatment and achieve a favorable result.
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