Evidence map›Paper›PMID 35492164›Full record

ArticleRSC advances2020

Electrochemical immunosensor based on AuBP@Pt nanostructure and AuPd-PDA nanozyme for ultrasensitive detection of APOE4.

Yibiao Liu, Guangli He, Huili Liu, Hang Yin, Fengli Gao, Jian Chen, Shouren Zhang, Baocheng Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Yibiao LiuDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.ORCID https://orcid.org/0000-0002-6118-665X
Guangli HeDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.
Huili LiuDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.
Hang YinDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.
Fengli GaoDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.
Jian ChenDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.ORCID https://orcid.org/0000-0002-3054-918X
Shouren ZhangDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.ORCID https://orcid.org/0000-0001-6661-6324
Baocheng YangDepartment of Henan Key Laboratory of Nanocomposites and Applications, Institute of Nanostructured Functional Materials, Huanghe Science and Technology College Zhengzhou 450006 China liuyibiao12345@126.com jianchen@infm.hhstu.edu.cn.
NanoComposix (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An ultrasensitive sandwich-type electrochemical immunosensor based on AuBP@Pt nanostructures and AuPd-PDA nanozyme was developed for the detection of apolipoprotein E4 (APOE4) which was an important risk factor for Alzheimer's disease (AD). In this work, gold nanobipyramid coated Pt (AuBP@Pt) nanostructures were prepared and applied to electrochemical immunosensors as a substrate material. AuBP@Pt nanostructures have advantages of electrical conductivity and large electroactive area, which could greatly increase electron transfer rate. In previous work, we designed AuPd alloy modified polydopamine (AuPd-PDA) nanozyme which catalyzed the decomposition of hydrogen peroxide (H

Identifiers

PMID35492164
PMCPMC9049899
OpenAlexW3008043182

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.