Evidence map›Paper›PMID 35492050›Full record

ArticleHardwareX2021

A low-cost uniaxial cell stretcher for six parallel wells.

Delf Kah, Alexander Winterl, Magdalena Přechová, Ulrike Schöler, Werner Schneider, Oliver Friedrich, Martin Gregor, Ben Fabry

Abstract read
In one paragraph

Article in HardwareX, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Cellular mechanisms of traumatic brain injury.npj biological physics and mechanics · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Quantitative Live-Cell CaMethods in molecular biology (Clifton, N.J.) · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Delf KahBiophysics Group, Department of Physics, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Alexander WinterlBiophysics Group, Department of Physics, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Magdalena PřechováLaboratory of Integrative Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Ulrike SchölerInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, FAU, Erlangen, Germany.
Werner SchneiderBiophysics Group, Department of Physics, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
Oliver FriedrichInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, FAU, Erlangen, Germany.
Martin GregorLaboratory of Integrative Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Ben FabryBiophysics Group, Department of Physics, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells in the lungs, the heart, and numerous other organs, are constantly exposed to dynamic forces and deformations. To mimic these dynamic mechanical loading conditions and to study the resulting cellular responses such as morphological changes or the activation of biochemical signaling pathways, cells are typically seeded on flexible 2D substrates that are uniaxially or biaxially stretched. Here, we present an open-source cell stretcher built from parts of an Anet A8 3D printer. The cell stretcher is controlled by a fully programmable open-source software using GCode and Python. Up to six flexible optically clear substrates can be stretched simultaneously, allowing for comparative multi-batch biological studies including microscopic image analysis. The cell yield from the cell culture area of 4 cm

Indexed as

3D printerCell MechanicsCell stretcherMechanosensingUniaxial stretchYAP

Identifiers

PMID35492050
PMCPMC9041267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.