Evidence map›Paper›PMID 35491834›Full record

ArticlemSphere2022

Selective Whole-Genome Amplification as a Tool to Enrich Specimens with Low Treponema pallidum Genomic DNA Copies for Whole-Genome Sequencing.

Charles M Thurlow, Sandeep J Joseph, Lilia Ganova-Raeva, Samantha S Katz, Lara Pereira, Cheng Chen, Alyssa Debra, Kendra Vilfort, Kimberly Workowski, Stephanie E Cohen and 10 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Complete genome sequences of twoMicrobiology resource announcements · 2025
    Article
  5. Article
  6. Review
  7. Molecular investigation ofMicrobiology spectrum · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. StrengtheningJournal of clinical microbiology · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Notes on syphilis vaccine development.Frontiers in immunology · 2022
    Review
  17. High-throughput nanopore sequencing ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Charles M ThurlowDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0003-3127-7558
Sandeep J JosephDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0003-0697-2487
Lilia Ganova-RaevaDivision of Viral Hepatitis, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Samantha S KatzDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Lara PereiraDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Cheng ChenDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Alyssa DebraDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Kendra VilfortDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Kimberly WorkowskiDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Stephanie E CohenSan Francisco Department of Public Healthgrid.410359.a, San Francisco, California, USA.
Hilary RenoSt. Louis County Sexual Health Clinic, St. Louis, Missouri, USA.
Yongcheng SunDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Mark BurroughsDivision of Scientific Resources, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Mili ShethDivision of Scientific Resources, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Kai-Hua ChiDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Damien DanavallDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Susan S PhilipDepartment of Medicine, Emory University, Atlanta, Georgia, USA.
Weiping CaoDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Ellen N KershDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0003-3819-0324
Allan PillayDivision of STD Prevention, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0001-5326-9490
Centers for Disease Control and Prevention · USEmory University · USSan Francisco Department of Public Health · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Downstream next-generation sequencing (NGS) of the syphilis spirochete Treponema pallidum subspecies

Indexed as

SyphilisTreponema pallidumAnimalsHigh-Throughput Nucleotide SequencingMetagenomicsRabbitsWhole Genome SequencingDNA enrichmentmetagenomicssyphilisTreponema pallidumwhole-genome sequencing

Identifiers

PMID35491834
PMCPMC9241506
OpenAlexW4225262866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.