ArticleJournal of Alzheimer's disease : JAD2022
Behavioral and Psychological Symptoms of Dementia in Different Dementia Disorders: A Large-Scale Study of 10,000 Individuals.
Article in Journal of Alzheimer's disease : JAD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 6 of them syntheses that pooled it.
What it found
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Who cites it
85 citing papers in PubMed, 6 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Barriers and facilitators to accessing and engaging with arts-based non-pharmacological interventions for people living with dementia: A systematic review.Dementia (London, England) · 2026Pooled it
- The use of care home environments to meet culture-specific needs of culturally and linguistically diverse residents with dementia: an integrative review using the ICF framework.International journal for equity in health · 2026Pooled it
- Pooled it
- The prevalence of apathy in Lewy body dementia: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Behavioral and psychological symptoms of dementia associated with vascular impairment: a systematic review and meta-analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Pooled it
- Topical Cellular/Tissue and Molecular Aspects Regarding Nonpharmacological Interventions in Alzheimer's Disease-A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Facial Emotion Recognition Ability May Improve in Alzheimer Disease: A Pilot Study.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2026Trial
- Effect of Virtual Reality-Based Mindfulness Program vs Audio-Guided Mindfulness on Depression, Sleep, and Quality of Life in Dementia Family Caregivers: An Exploratory Randomized Controlled Trial.International journal of medical sciences · 2026Trial
- Feasibility and tolerability of low-dose lithium for the treatment of agitation and abnormal motor behaviors in Frontotemporal Dementia.International review of psychiatry (Abingdon, England) · 2025Trial
- [Pain management in people with dementia : Recognizing pain and providing supportive care].Schmerz (Berlin, Germany) · 2026Article
- Agitation in dementia: Evidence-based consensus recommendations.Journal of the Chinese Medical Association : JCMA · 2026Review
- The Relationship Between Social Cognition and Social Behavior in Patients with a Neurodegenerative Disease: A Systematic Review and Meta-Analysis.Neuropsychology review · 2026Review
- Association of Participation in the Collaborative Care Team With Behavioral and Psychological Symptoms of Dementia and Caregiver Distress.Brain and behavior · 2026Article
- Detecting cognitive impairment and psychological well-being among older adults.Machine learning. Health · 2026Article
- Prediction of Antipsychotic Drug Doses for BPSD in Alzheimer's Disease Using Deep Learning Techniques.Diagnostics (Basel, Switzerland) · 2026Article
- Theoretical impact of a mobile team dedicated to patients with Alzheimer's disease and related dementias on medication exposure in community-dwelling older patients (MEMORIAS study).BMC geriatrics · 2026Article
- Glial Cells in Behavioral and Psychological Symptoms of Alzheimer's Disease.International journal of molecular sciences · 2026Review
- Aspects of providing care for individuals with vascular dementia - a caregiver's perspective.BMC geriatrics · 2026Article
- Potential of ASCOT-Carer for evaluating the quality of life of family caregivers for patients with Alzheimer's disease in Japan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum.Molecular psychiatry · 2026Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe majority of individuals with dementia will suffer from behavioral and psychological symptoms of dementia (BPSD). These symptoms contribute to functional impairment and caregiver burden.
objectiveTo characterize BPSD in Alzheimer's disease (AD), vascular dementia (VaD), mixed (Mixed) dementia, Parkinson's disease dementia (PDD), dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), and unspecified dementia in individuals residing in long-term care facilities.
methodsWe included 10,405 individuals with dementia living in long-term care facilities from the Swedish registry for cognitive/dementia disorders (SveDem) and the Swedish BPSD registry. BPSD was assessed with the Neuropsychiatric Inventory - Nursing Home Version (NPI-NH). Multivariate logistic regression models were used to evaluate the associations between dementia diagnoses and different BPSDs.
resultsThe most common symptoms were aberrant motor behavior, agitation, and irritability. Compared to AD, we found a lower risk of delusions (in FTD, unspecified dementia), hallucinations (FTD), agitation (VaD, PDD, unspecified dementia), elation/euphoria (DLB), anxiety (Mixed, VaD, unspecified dementia), disinhibition (in PDD), irritability (in DLB, FTD, unspecified dementia), aberrant motor behavior (Mixed, VaD, unspecified dementia), and sleep and night-time behavior changes (unspecified dementia). Higher risk of delusions (DLB), hallucinations (DLB, PDD), apathy (VaD, FTD), disinhibition (FTD), and appetite and eating abnormalities (FTD) were also found in comparison to AD.
conclusionAlthough individuals in our sample were diagnosed with different dementia disorders, they all exhibited aberrant motor behavior, agitation, and irritability. This suggests common underlying psychosocial or biological mechanisms. We recommend prioritizing these symptoms while planning interventions in long-term care facilities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.