Evidence map›Paper›PMID 35491662›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2023

Combined technique as first approach in mechanical thrombectomy: Efficacy and safety of REACT catheter combined with stent retriever.

Manuel Requena, Carlos Piñana, Marta Olive-Gadea, David Hernández, Sandra Boned, Marta De Dios, Marc Rodrigo, Eila Rivera, Marián Muchada, José Luis Cuevas and 6 more

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Improved catheter delivery for aspiration thrombectomy using Tenzing 7 ledge reducing catheter and FreeClimb 70.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  2. Article
  3. Combined technique versus stent-retriever alone: Interaction analysis of angioarchitectural and technical features.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Contact Aspiration Alone or Combined With Stent Retriever Thrombectomy for Middle Cerebral Artery Large Vessel Occlusion.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Manuel RequenaUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0002-5671-6484
Carlos PiñanaNeurorradiologia Intervencionista, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0001-7316-6202
Marta Olive-GadeaUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
David HernándezNeurorradiologia Intervencionista, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Sandra BonedUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0002-9878-7280
Marta De DiosNeurorradiologia Intervencionista, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Marc RodrigoUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Eila RiveraNeurorradiologia Intervencionista, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Marián MuchadaUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
José Luis CuevasNeurorradiologia Intervencionista, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0002-4504-2277
Marta RubieraUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Álvaro García-TornelUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Laura Ludovica GramegnaIRCCS Istituto delle Scienze Neurologiche di Bologna, Functional and Molecular Neuroimaging Unit, Bologna, Italy.ORCID 0000-0002-9192-5994
Carlos MolinaUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Marc RiboUnitat d'Ictus, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Alejandro TomaselloNeurorradiologia Intervencionista, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0002-6736-1535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMechanical thrombectomy (MT) with combined treatment including both a stent retriever and distal aspiration catheter may improve recanalization rates in patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Here, we evaluated the effectiveness and safety of the REACT aspiration catheter used with a stent retriever.

methodsThis prospective study included consecutive adult patients who underwent MT with a combined technique using REACT 68 and/or 71 between June 2020 and July 2021. The primary endpoints were final and first pass mTICI 2b-3 and mTICI 2c-3 recanalization. Analysis was performed after first pass and after each attempt. Secondary safety outcomes included procedural complications, symptomatic intracranial hemorrhage (sICH) at 24 h, in-hospital mortality, and 90-day functional independence (modified Rankin Scale [mRS] 0-2).

resultsA total of 102 patients were included (median age 78; IQR: 73-87; 50.0% female). At baseline, median NIHSS score was 19 (IQR: 11-21), and ASPECTS was 9 (IQR: 8-10). Final mTICI 2b-3 recanalization was achieved in 91 (89.2%) patients and mTICI 2c-3 was achieved in 66 (64.7%). At first pass, mTICI 2b-3 was achieved in 55 (53.9%) patients, and mTICI 2c-3 in 37 (36.3%). The rate of procedural complications was 3.9% (4/102), sICH was 6.8% (7/102), in-hospital mortality was 12.7% (13/102), and 90-day functional independence was 35.6% (36/102).

conclusionA combined MT technique using a stent retriever and REACT catheter resulted in a high rate of successful recanalization and first pass recanalization in a sample of consecutive patients with AIS due to LVO in clinical use.

Indexed as

Brain IschemiaIschemic StrokeStrokeAgedCathetersFemaleHumansIntracranial HemorrhagesMaleProspective StudiesRetrospective StudiesStentsThrombectomyTreatment OutcomeAcute strokeendovascular treatmentmechanical thrombectomy

Identifiers

PMID35491662
PMCPMC10549706

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.