Evidence map›Paper›PMID 35491423›Full record

ArticleBMC biology2022

The steroid hormone estriol (E

Yuping Zhou, Baoxia Gu, Geraldine Brichant, Jay Prakash Singh, Huan Yang, Hao Chang, Yanding Zhao, Chao Cheng, Zhong-Wu Liu, Myles H Alderman and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
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  13. Imprinting and Reproductive Health: A Toxicological Perspective.International journal of molecular sciences · 2023
    Review
  14. Review
  15. Biological Sex and Pregnancy Affect Influenza Pathogenesis and Vaccination.Current topics in microbiology and immunology · 2023
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Yuping ZhouDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Baoxia GuDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Geraldine BrichantDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Jay Prakash SinghDepartment of Comparative Medicine and of Cellular and Molecular Physiology, Yale University, New Haven, CT, 06520, USA.
Huan YangDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Hao ChangDepartment of Genetics, Yale University, New Haven, CT, 06520, USA.
Yanding ZhaoDepartment of Medicine, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Chao ChengDepartment of Medicine, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.
Zhong-Wu LiuPresent Address: Reproductive Medicine Center of Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China, 450003.
Myles H AldermanDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Lingeng LuDepartment of Chronic Disease Epidemiology, Yale University, New Haven, CT, 06520, USA.
Xiaoyong YangDepartment of Comparative Medicine and of Cellular and Molecular Physiology, Yale University, New Haven, CT, 06520, USA.
Xiao-Bing GaoDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA.
Hugh S TaylorDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, Yale University, 333 Cedar Street, New Haven, CT, 06520, USA. hugh.taylor@yale.edu.ORCID 0000-0003-1720-8310
Yale University · USBaylor College of Medicine · USYale Cancer Center · USZhengzhou University · CN

Funding

Environmental Estrogen Induced Epigenetic Alteration of Uterine Stem CellsR01HD076422 · NICHD · YALE UNIVERSITY · PI TAYLOR, HUGH SMITH · 2012 to 2016
$2.0M
NICHD NIH HHS R01 HD076422
6 · The paper itself

Abstract

backgroundEstriol (E

resultsWe administered E

conclusionsWe identify an unexpected functional role for E

Indexed as

EstrogensReceptors, EstrogenAnimalsBrainEpigenesis, GeneticEstriolFemaleFetusMaleMicePregnancySteroidsEstriolEstrogensReceptors, EstrogenSteroidsBehaviorDevelopmental programmingDNA methylationE3EpigeneticsEstriolPregnancyReproduction

Identifiers

PMID35491423
PMCPMC9059368
OpenAlexW4225263705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.