Evidence map›Paper›PMID 35491306›Full record

ReviewTrends in cell biology2022

Mechanical regulation of cell-cycle progression and division.

Vivek K Gupta, Ovijit Chaudhuri

Open access · greenAbstract readReview
In one paragraph

Review in Trends in cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  3. Postbiotic potential of heat-inactivated Limosilactobacillus reuteri and its cell-free supernatant in protecting intestinal health of zebrafish.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  18. Piezo1, F-Actin Remodeling, and Podocyte Survival and Regeneration.Journal of the American Society of Nephrology : JASN · 2025
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vivek K GuptaDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA.
Ovijit ChaudhuriDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA.. Electronic address: chaudhuri@stanford.edu.
Stanford University · US

Funding

Role of extracellular matrix malleability in mediating breast cancer cell invasion and migrationR37CA214136 · NCI · STANFORD UNIVERSITY · PI CHAUDHURI, OVIJIT · 2018 to 2024
$2.5M
NCI NIH HHS R37 CA214136
6 · The paper itself

Abstract

Cell-cycle progression and division are fundamental biological processes in animal cells, and their biochemical regulation has been extensively studied. An emerging body of work has revealed how mechanical interactions of cells with their microenvironment in tissues, including with the extracellular matrix (ECM) and neighboring cells, also plays a crucial role in regulating cell-cycle progression and division. We review recent work on how cells interpret physical cues and alter their mechanics to promote cell-cycle progression and initiate cell division, and then on how dividing cells generate forces on their surrounding microenvironment to successfully divide. Finally, the article ends by discussing how force generation during division potentially contributes to larger tissue-scale processes involved in development and homeostasis.

Indexed as

Extracellular MatrixMechanotransduction, CellularAnimalsCell DivisionHomeostasiscell cyclecell divisionextracellular matrixforce generationmechanotransductionmicroenvironmentmitosis

Identifiers

PMID35491306
PMCPMC9378598
OpenAlexW4225164000

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.