Evidence map›Paper›PMID 35490716›Full record

ArticleJournal of the American Medical Directors Association2022

Medications Associated With Geriatric Syndromes (MAGS) and Hospitalization Risk in Home Health Care Patients.

Jinjiao Wang, Jenny Y Shen, Fang Yu, Yeates Conwell, Kobi Nathan, Avantika S Shah, Sandra F Simmons, Yue Li, Erika Ramsdale, Thomas V Caprio

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Challenges in Deprescribing among Older Adults in Post-Acute Care Transitions to Home.Journal of the American Medical Directors Association · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Jinjiao WangHubbard Center for Nursing Research on Aging, University of Rochester, School of Nursing, Rochester, NY, USA.
Jenny Y ShenUniversity of Rochester Medical Center, Department of Medicine, Rochester, NY, USA.
Fang YuArizona State University, Edson College of Nursing and Health Innovation, Phoenix, AZ, USA.
Yeates ConwellUniversity of Rochester Medical Center, Department of Psychiatry, Rochester, NY, USA.
Kobi NathanDivision of Geriatrics & Aging, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA; St. John Fisher College, Wegmans School of Pharmacy, Rochester, NY, USA.
Avantika S ShahDivision of Geriatrics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Center for Quality Aging, Nashville, TN, USA.
Sandra F SimmonsDivision of Geriatrics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Center for Quality Aging, Nashville, TN, USA; Geriatric Research, Education and Clinical Center (GRECC), VA Tennessee Valley Healthcare System, Nashville, TN, USA.
Yue LiDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, USA.
Erika RamsdaleDepartment of Medicine, Division of Hematology/Oncology, University of Rochester Medical Center, Rochester, NY, USA.
Thomas V CaprioDivision of Geriatrics & Aging, Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA; University of Rochester Medical Home Care, University of Rochester Medical Center, Rochester, NY, USA; Finger Lakes Geriatric Education Center, University of Rochester Medical Center, Rochester, NY, USA.
University of Rochester Medical Center · USArizona State University · USGeriatric Research Education and Clinical Center · USSt. John Fisher College · USUniversity of Rochester · USVanderbilt University Medical Center · US

Funding

U.S. Deprescribing Research NetworkR24AG064025 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI BOYD, CYNTHIA MELINDA, STEINMAN, MICHAEL A. · 2019 to 2023
$9.9M
NIA NIH HHS R24 AG064025
6 · The paper itself

Abstract

objectivesPolypharmacy is common in home health care (HHC). This study examined the prevalence of medications associated with geriatric syndromes (MAGS), its predictors, and association with subsequent hospitalization in HHC.

designAnalysis of HHC electronic medical records, the Outcome and Assessment Information Set (OASIS), and Medicare HHC claims. SETTING AND

participantsA total of 6882 adults ≥65 years old receiving HHC in 2019 from a large, not-for-profit home health agency serving multiple counties in New York State. MEASURES: MAGS use was identified from active medications reconciled during HHC visits (HHC electronic medical records). MAGS use was operationalized as count and in quartiles. Hospitalization during the HHC episode was operationalized as a time-to-event variable (ie, number of days from HHC admission to hospitalization). We used regression analyses to identify predictors of MAGS use, and survival analyses to examine the association between MAGS and hospitalization.

resultsNearly all (98%) of the HHC patients used at least 1 MAGS and 41% of all active medications used by the sample were MAGS. More MAGS use was found in HHC patients who were community-referred, taking more medications, and having more diagnoses, depressive symptoms, and functional limitations. Adjusted for covariates, higher MAGS quartiles were not independently associated with the risk of hospitalization, but higher MAGS quartiles combined with multimorbidity (ie, having ≥10 diagnoses) were associated with a 2.3-fold increase in hospitalization risk (hazard ratio 2.24; 95% confidence interval: 1.61-3.13; P < .001), relative to the lowest quartile of MAGS use and having <10 diagnoses. CONCLUSIONS AND IMPLICATIONS: More than 40% of medications taken by HHC patients are MAGS. Multimorbidity and MAGS use collectively increased the risk of hospitalization by up to 2.3 times. HHC clinicians should carefully review patients' medications and use information about MAGS to facilitate discussion about deprescribing with patients and their prescribers.

Indexed as

Home Care ServicesMedicareAgedGeriatric AssessmentHospitalizationHumansProportional Hazards ModelsUnited StatesdeprescribingHome health caremedications associated with geriatric syndromespolypharmacy

Identifiers

PMID35490716
PMCPMC9547843
OpenAlexW4225323868

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.