ArticleBMC musculoskeletal disorders2022
Effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair.
Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 3 citations in OpenAlex.
- The Effect of Lower Limb Pressotherapy Treatment on Selected Rheological and Biochemical Indices of Blood in Young, Healthy Women.Journal of clinical medicine · 2024Article
- Where Does Blood Flow Restriction Fit in the Toolbox of Athletic Development? A Narrative Review of the Proposed Mechanisms and Potential Applications.Sports medicine (Auckland, N.Z.) · 2023Review
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Authors and funding
7 authors at 1 institution in 1 country.
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Abstract
backgroundTo estimate the effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair in an animal model.
methodsFive mm radial bone defect in length was made in 64 mature New Zealand rabbits and all animals randomly assigned into four groups: Group A (control group without compression), Group B (5-7 kPa intensity), Group C (8-10 kPa intensity) and Group D (11-13 kPa intensity). On the fourth day after surgery, their legs were intermittently pneumatic compressed for 4 weeks. The stimulation lasted 30 min every day and the frequency of compression was 15 Hz. New bone formation in 4 groups was evaluated by gross observation, X-ray, Micro-CT, and histological staining at 2 and 4 weeks after surgery.
resultThere was more new bony callus in the bone defect in group C than in other groups by gross observation and X-ray radiography at 2 and 4 weeks. The Micro-CT results showed more new bony callus, bone trabecula and higher bone mineral density in group C. Fluorescent labeling results showed the speed of new bone formation in Group C was faster than that in other groups, among which the control group had the slowest speed of new bone formation. The result of histology had shown that the trabeculae in bone callus in group C had a regular form, the trabeculae were wide and had a more become osteoblast around them.
conclusionThe intermittent pneumatic soft-tissue compression can accelerate new bone formation of bone defects and the optimal intensity is 8-10 kPa for repairing the rabbit radial bone defect.
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