Evidence map›Paper›PMID 35489241›Full record

ArticleRedox biology2022

Mycobacterium tuberculosis DosS binds H

Ritesh R Sevalkar, Joel N Glasgow, Martín Pettinati, Marcelo A Marti, Vineel P Reddy, Swati Basu, Elmira Alipour, Daniel B Kim-Shapiro, Dario A Estrin, Jack R Lancaster and 1 more

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Metalloprotein enabled redox signal transduction in microbes.Current opinion in chemical biology · 2023
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Ritesh R SevalkarDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Joel N GlasgowDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: jng@uab.edu.
Martín PettinatiUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Inorgánica, Analítica y Química Física, Buenos Aires, Argentina; CONICET-Universidad de Buenos Aires, Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Buenos Aires, Argentina.
Marcelo A MartiUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Biológica, Buenos Aires, Argentina; CONICET-Universidad de Buenos Aires, Instituto de Química Biológica (IQUIBICEN), Buenos Aires, Argentina.
Vineel P ReddyDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Swati BasuDepartment of Physics, Wake Forest University, Winston-Salem, NC, USA.
Elmira AlipourDepartment of Physics, Wake Forest University, Winston-Salem, NC, USA.
Daniel B Kim-ShapiroDepartment of Physics, Wake Forest University, Winston-Salem, NC, USA.
Dario A EstrinUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Inorgánica, Analítica y Química Física, Buenos Aires, Argentina; CONICET-Universidad de Buenos Aires, Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Buenos Aires, Argentina.
Jack R LancasterDepartment of Pharmacology & Chemical Biology, Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Adrie J C SteynDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA; Centers for AIDS Research and Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA; Africa Health Research Institute, University of KwaZulu-Natal, Durban, South Africa. Electronic address: asteyn@uab.edu.
University of Alabama at Birmingham · USConsejo Nacional de Investigaciones Científicas y Técnicas · ARWake Forest University · USUniversity of Pittsburgh · US

Funding

Construction/SEBLAB/Regional Biocontainment LaboratoryUC6AI058599 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MARCHASE, RICHARD BANFIELD · 2003 to 2006
$22.0M
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide HomeostasisR01HL098032 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Mark T Gladwin · 2009 to 2026
$12.5M
Hydrogen Sulfide and Tuberculosis DiseaseR01AI134810 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STEYN, ADRIE JC · 2018 to 2021
$2.2M
Heme oxygenase-1 and the bioenergetic threshold of latent TB and HIV co-infectionR01AI111940 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STEYN, ADRIE JC · 2015 to 2019
$2.0M
METABOLIC REPROGRAMMING OF T CELL ENERGY METABOLISM IN TUBERCULOSIS AND HIVR33AI138280 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STEYN, ADRIE JC · 2020 to 2023
$2.0M
METABOLIC REPROGRAMMING OF T CELL ENERGY METABOLISM IN TUBERCULOSIS AND HIVR61AI138280 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STEYN, ADRIE JC · 2018 to 2019
$1.0M
NHLBI NIH HHS R01 HL098032NIAID NIH HHS R01 AI111940NIAID NIH HHS R01 AI134810NIAID NIH HHS R33 AI138280NIAID NIH HHS R61 AI138280NIAID NIH HHS UC6 AI058599
6 · The paper itself

Abstract

Mycobacterium tuberculosis (Mtb) senses and responds to host-derived gasotransmitters NO and CO via heme-containing sensor kinases DosS and DosT and the response regulator DosR. Hydrogen sulfide (H

Indexed as

GasotransmittersMycobacterium tuberculosisAnimalsBacterial ProteinsDioctyl Sulfosuccinic AcidGene Expression Regulation, BacterialHemeIronMammalsProtamine KinaseRegulonBacterial ProteinsDioctyl Sulfosuccinic AcidGasotransmittersHemeIronProtamine KinaseDormancy regulonDosSHydrogen sulfideTuberculosisTwo-component system

Identifiers

PMID35489241
PMCPMC9062744
OpenAlexW4224285798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.