Evidence map›Paper›PMID 35489042›Full record

ArticleChemMedChem2022

Promising Therapeutic Approach for SARS-CoV-2 Infections by Using a Rutin-Based Combination Therapy.

Monika Mazik

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in ChemMedChem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Bioactive Compounds ofInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Crystal structures of 3,4,5-tri-phenyl-toluene and 3,4,5-tri-phenyl-benzyl bromide.Acta crystallographica. Section E, Crystallographic communications · 2025
    Article
  4. Identification ofMolecules (Basel, Switzerland) · 2025
    Article
  5. IntegratedCurrent medicinal chemistry · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Monika MazikInstitut für Organische Chemie, Technische Universität Bergakademie Freiberg, Leipziger Straße 29, 09599, Freiberg, Germany.ORCID 0000-0003-3571-7899
TU Bergakademie Freiberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of new therapeutic approaches for SARS-CoV-2 infections is of particular current importance. The combination therapy proposed here is based on already proven, safe and inexpensive compounds. The natural compound rutin, one of the six therapy components, has the potential to inhibit both viral and host cell targets. In addition, this therapy involves the use of acetylsalicylic acid, vitamin C and vitamin D

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsHumansRutinSARS-CoV-2Antiviral AgentsRutinantioxidantsantiviral agentsflavonoidsmolecular recognitionNatural productsnoncovalent interactionsvirusesvitamins

Identifiers

PMID35489042
PMCPMC9321678
OpenAlexW4225137847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.