ArticleAnnals of clinical and translational neurology2022
Hyperventilation-induced focal seizures in adults: think autoimmune encephalitis.
Article in Annals of clinical and translational neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Diagnosing autoimmune encephalitis in psychiatry: clinical recommendations and unresolved challenges from the GENERATE network.Molecular psychiatry · 2026Review
- Not All Spikes Are Equal.Journal of clinical medicine · 2025Review
- Heartbeat-evoked potentials following voluntary hyperventilation in epilepsy patients: respiratory influences on cardiac interoception.Frontiers in neuroscience · 2024Article
- Seizures, Epilepsy, and NORSE Secondary to Autoimmune Encephalitis: A Practical Guide for Clinicians.Biomedicines · 2022Review
- Is There a Continuum Between Acute Symptomatic Seizures Secondary to Autoimmune Encephalitis and Autoimmune-Associated Epilepsy?Epilepsy currentsArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Case reports have described rare patients with autoimmune encephalitis in whom focal seizures could be reliably provoked by hyperventilation. With the hypothesis that this phenomenon may have diagnostic significance, all cases of hyperventilation-induced focal seizures identified during ~10,000 consecutive routine electroencephalography (EEG) studies were reviewed, and corresponding diagnoses established. Seven EEG recordings, in six patients, contained focal hyperventilation-induced seizures, each of temporal lobe onset. All patients were diagnosed with autoimmune encephalitis, in two cases after EEG; five had voltage-gated potassium channel complex autoantibodies. Although rare, a hyperventilation-induced focal seizure during EEG in an adult should raise concern for autoimmune encephalitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.