Evidence map›Paper›PMID 35488682›Full record

ArticleLung India : official organ of Indian Chest Society

Silent Hypoxia in Coronavirus disease-2019: Is it more dangerous? -A retrospective cohort study.

Prashant Sirohiya, Arunmozhimaran Elavarasi, Hari Krishna Raju Sagiraju, Madhusmita Baruah, Nishkarsh Gupta, Rohit Kumar Garg, Saurav Sekhar Paul, Brajesh Kumar Ratre, Ram Singh, Balbir Kumar and 17 more

Open access · diamondAbstract read
In one paragraph

Article in Lung India : official organ of Indian Chest Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. COVID-19 and Gut Injury.Nutrients · 2022
    Review
  5. Review
  6. The Effectiveness of SARS-CoV-2 Vaccination in Preventing Severe Illness and Death - Real-world Data from a Cohort of Patients Hospitalized with COVID-19.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
  7. Article
  8. Happy hypoxemia in COVID-19 patients: Fact or myth?Journal of anaesthesiology, clinical pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 1 institution in 1 country.

Prashant SirohiyaDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Arunmozhimaran ElavarasiDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Hari Krishna Raju SagirajuDepartment of Preventive Oncology, All India Institute of Medical Sciences, New Delhi, India.
Madhusmita BaruahDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Nishkarsh GuptaDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Rohit Kumar GargDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Saurav Sekhar PaulDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Brajesh Kumar RatreDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Ram SinghDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Balbir KumarDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Saurabh VigDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Anuja PanditDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Abhishek KumarDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Rakesh GargDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Ved Prakash MeenaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Saurabh MittalDepartment of Pulmonary Medicine, Critical Care and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.
Saurabh PahujaDepartment of Pulmonary Medicine, Critical Care and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.
Nupur DasDepartment of Laboratory Oncology, All India Institute of Medical Sciences, New Delhi, India.
Tanima DwivediDepartment of Laboratory Oncology, All India Institute of Medical Sciences, New Delhi, India.
Ritu GuptaDepartment of Laboratory Oncology, All India Institute of Medical Sciences, New Delhi, India.
Sunil KumarDepartment of Surgical Oncology, All India Institute of Medical Sciences, New Delhi, India.
Manisha PandeyDepartment of Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Abhinav MishraDepartment of Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Karanvir Singh MatharooDepartment of Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
Anant MohanDepartment of Pulmonary Medicine, Critical Care and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.
Randeep GuleriaDepartment of Pulmonary Medicine, Critical Care and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India.
Sushma BhatnagarDepartment of Onco-anesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypoxia in patients with COVID-19 is one of the strongest predictors of mortality. Silent hypoxia is characterised by the presence of hypoxia without dyspnoea. Silent hypoxia has been shown to affect the outcome in previous studies. Methods: This was a retrospective study of a cohort of patients with SARS-CoV-2 infection who were hypoxic at presentation. Clinical, laboratory and treatment parameters in patients with silent hypoxia and dyspnoeic hypoxia were compared. Multivariate logistic regression models were fitted to identify the factors predicting mortality. Results: Among 2080 patients with COVID-19 admitted to our hospital, 811 patients were hypoxic with SpO Conclusion: Silent hypoxia may be the only presenting feature of COVID-19. As the case fatality rate is comparable between silent and dyspnoeic hypoxia, it should be recognised early and treated as aggressively. Because home isolation is recommended in patients with COVID-19, it is essential to use pulse oximetry in the home setting to identify these patients.

Indexed as

Asymptomatic hypoxiacase fatality ratecoronavirus diseaseCOVID-19happy hypoxiahypoxemia hypoxiaSARS-CoV-2silent hypoxia

Identifiers

PMID35488682
PMCPMC9200195
OpenAlexW4225255221

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.