ArticleHuman brain mapping2022
Spindle-slow oscillation coupling correlates with memory performance and connectivity changes in a hippocampal network after sleep.
Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Pooled it
- An Electroencephalographic Study of Sleep Spindle and Infraslow Oscillation in Children With Autism Spectrum Disorder.Journal of sleep research · 2026Article
- Classifying Sleep Slow Oscillations in Low Density EEG.Neuroinformatics · 2026Article
- From Electron Imbalance to Network Collapse: Decoding the Redox Code of Ischemic Stroke for Biomarker-Guided Precision Neuroprotection.International journal of molecular sciences · 2025Review
- The Space-Time Organisation of Sleep Slow Oscillations as Potential Biomarker for Hypersomnolence.Journal of sleep research · 2025Article
- Phase-Amplitude Coupling of NREM Sleep Oscillations Shows Between-Night Stability and is Related to Overnight Memory Gains.The European journal of neuroscience · 2025Article
- Slow Oscillation-Spindle Coupling Predicts Sequence-Based Language Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Differential expression of spatiotemporal sleep spindle clusters in aging.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Development of slow oscillation-spindle coupling from infancy to toddlerhood.Sleep advances : a journal of the Sleep Research Society · 2024Article
- A classification-based generative approach to selective targeting of global slow oscillations during sleep.Frontiers in human neuroscience · 2024Article
- Possible mechanisms to improve sleep spindles via closed loop stimulation during slow wave sleep: A computational study.PloS one · 2024Article
- Sleep spindle maturity promotes slow oscillation-spindle coupling across child and adolescent development.eLife · 2023Article
- CBD lengthens sleep but shortens ripples and leads to intact simple but worse cumulative memory.iScience · 2023Article
- Memory ability and retention performance relate differentially to sleep depth and spindle type.iScience · 2023Article
- The Hierarchy of Coupled Sleep Oscillations Reverses with Aging in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- An implementation of integrated information theory in resting-state fMRI.Communications biology · 2023Article
- Increased cortical plasticity leads to memory interference and enhanced hippocampal-cortical interactions.eLife · 2023Article
- Spindle-slow oscillation coupling correlates with memory performance and connectivity changes in a hippocampal network after sleep.Human brain mapping · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After experiences are encoded, post-encoding reactivations during sleep have been proposed to mediate long-term memory consolidation. Spindle-slow oscillation coupling during NREM sleep is a candidate mechanism through which a hippocampal-cortical dialogue may strengthen a newly formed memory engram. Here, we investigated the role of fast spindle- and slow spindle-slow oscillation coupling in the consolidation of spatial memory in humans with a virtual watermaze task involving allocentric and egocentric learning strategies. Furthermore, we analyzed how resting-state functional connectivity evolved across learning, consolidation, and retrieval of this task using a data-driven approach. Our results show task-related connectivity changes in the executive control network, the default mode network, and the hippocampal network at post-task rest. The hippocampal network could further be divided into two subnetworks of which only one showed modulation by sleep. Decreased functional connectivity in this subnetwork was associated with higher spindle-slow oscillation coupling power, which was also related to better memory performance at test. Overall, this study contributes to a more holistic understanding of the functional resting-state networks and the mechanisms during sleep associated to spatial memory consolidation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.