Evidence map›Paper›PMID 35488347›Full record

ArticleWorld journal of surgical oncology2022

Prognostic significance of preoperative systemic inflammation response index in newly diagnosed glioblastoma patients underwent gross total resection: a propensity score matching analysis.

Zhihao Wang, Junhong Li, Yunbo Yuan, Tengfei Li, Mingrong Zuo, Yanhui Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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  12. An S-like curve relationship between systemic inflammation response index (SIRI) and respiratory failure in GBS patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhihao WangDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, People's Republic of China.
Junhong LiDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, People's Republic of China.
Yunbo YuanDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, People's Republic of China.
Tengfei LiDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, People's Republic of China.
Mingrong ZuoDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, People's Republic of China.
Yanhui LiuDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, People's Republic of China. liuyh@scu.edu.cn.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlioblastoma (GBM) is the most frequent and lethal brain tumor, which possesses highly malignant characteristics and predominates in elder patients. Systemic inflammatory response index (SIRI) is a novel prognostic marker from peripheral blood, which is defined as neutrophil count × monocyte count/lymphocyte count. In the current research, we aim to explore the relationship between SIRI and newly diagnosed GBM underwent gross total resection (GTR).

methodsA retrospective analysis was conducted on consecutive newly diagnosed GBM patients underwent operation at West China Hospital from March 2015 to January 2019. X-tile software was used to determine the optimal cut-off values of SIRI, and neutrophil to lymphocyte ratio (NLR). All statistical analyses were performed using SPSS software and R software. Propensity score matching (PSM) was conducted to adjust for imbalance of all potential confounding covariates.

resultsThe current research included a total of 291 consecutive newly diagnosed GBM patients underwent gross total resection. Among them, 186 were male patients and 105 were female patients. In original cohort, only gender was evidently related to SIRI level. SIRI and NLR were independent prognostic indicators both in original cohort and PSM cohort. Prognostic models based on the independent prognostic factors were established, and prognostic capacity of Model SIRI was superior to Model NLR.

conclusionIn the current research, SIRI was determined to be an independent prognostic indicator for GBM. And the prognostic predictive ability of SIRI was stronger than NLR.

Indexed as

GlioblastomaAgedFemaleHumansInflammationMalePrognosisPropensity ScoreRetrospective StudiesGlioblastoma (GBM)Gross total resection (GTR)Neutrophil to lymphocyte ratio (NLR)PrognosisSystemic inflammation response index (SIRI)

Identifiers

PMID35488347
PMCPMC9052476
OpenAlexW4225154683

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.