Evidence map›Paper›PMID 35488333›Full record

ArticleBMC urology2022

Safe provision of systemic anti-cancer treatment for urological cancer patients during COVID-19: a tertiary centre experience in the first wave of COVID-19.

Alfred Chung Pui So, Christina Karampera, Muhammad Khan, Beth Russell, Charlotte Moss, Maria J Monroy-Iglesias, Kiruthikah Thillai, Debra Hannah Josephs, Elias Pintus, Sarah Rudman and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Alfred Chung Pui SoDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Christina KaramperaDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Muhammad KhanDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Beth RussellTranslational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9RT, UK.
Charlotte MossTranslational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9RT, UK.
Maria J Monroy-IglesiasTranslational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9RT, UK.
Kiruthikah ThillaiDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Debra Hannah JosephsDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Elias PintusDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Sarah RudmanDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Mieke Van HemelrijckTranslational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King's College London, London, SE1 9RT, UK.
Saoirse DollyDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK.
Deborah EntingDepartment of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT, UK. deborah.enting@gstt.nhs.uk.
Guy's and St Thomas' NHS Foundation Trust · GBKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSafe provision of systemic anti-cancer treatment (SACT) during the COVID-19 pandemic remains an ongoing concern amongst clinicians.

methodsRetrospective analysis on uro-oncology patients who continued or started SACT between 1st March and 31st May 2020 during the pandemic (with 2019 as a comparator).

results441 patients received SACT in 2020 (292 prostate, 101 renal, 38 urothelial, 10 testicular) compared to 518 patients in 2019 (340 prostate, 121 renal, 42 urothelial, 15 testicular). In 2020, there were 75.00% fewer patients with stage 3 cancers receiving SACT (p < 0.0001) and 94.44% fewer patients receiving radical treatment (p = 0.00194). The number of patients started on a new line of SACT was similar between both years (118 in 2019 vs 102 in 2020; p = 0.898) but with 53.45% fewer patients started on chemotherapy in 2020 (p < 0.001). Overall, 5 patients tested positive for COVID-19 (one asymptomatic, one mild, two moderate, one severe resulting in death). Compared to 2019, 30-day mortality was similar (1.69% in 2019 vs 0.98% in 2020; p = 0.649) whereas 6-month mortality was lower (9.32% in 2019 vs 1.96% in 2020; p = 0.0209) in 2020.

conclusionThis study suggests that delivery of SACT to uro-oncology patients during COVID-19 pandemic may be safe in high-incidence areas with appropriate risk-reduction strategies.

Indexed as

COVID-19Urologic NeoplasmsFemaleHumansImmunotherapyMalePandemicsRetrospective Studies

Identifiers

PMID35488333
PMCPMC9051846
OpenAlexW4225259849

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.