Evidence map›Paper›PMID 35488271›Full record

ArticleJournal of neuroinflammation2022

CD4

Mahdia Benkhoucha, Ngoc Lan Tran, Gautier Breville, Isis Senoner, Paul F Bradfield, Thalia Papayannopoulou, Doron Merkler, Thomas Korn, Patrice H Lalive

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroinflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Pro-Inflammatory c-MetAnnals of neurology · 2026
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Mahdia BenkhouchaDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Ngoc Lan TranDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Gautier BrevilleDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Isis SenonerDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Paul F BradfieldMesenFlow Technologies SARL, Chemin des Aulx 14, Geneva, Switzerland.
Thalia PapayannopoulouDivision of Hematology, Department of Medicine, University of Washington, Seattle, WA, USA.
Doron MerklerDivision of Clinical Pathology, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Thomas KornDepartment of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Patrice H LaliveDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland. patrice.lalive@hcuge.ch.ORCID http://orcid.org/0000-0003-0607-5778
University of Geneva · CHTUM Klinikum · DEUniversity of Washington · US

Funding

European Research Council CoG647215German Research Council EXC2145-390857198German Research Council SFB1054-B06German Research Council TR128-A07German Research Council TR128-A12German Research Council TR274-A01Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung Grant 310030_176078
6 · The paper itself

Abstract

objectivec-Met, a tyrosine kinase receptor, is the unique receptor for hepatocyte growth factor (HGF). The HGF/c-Met axis is reported to modulate cell migration, maturation, cytokine production, and antigen presentation. Here, we report that CD4

methodsc-Met expression by CD4

resultsCD4

Indexed as

Encephalomyelitis, Autoimmune, ExperimentalMultiple SclerosisAnimalsHumansIntegrin alpha4MiceMice, Inbred C57BLNeuroinflammatory DiseasesTh17 CellsIntegrin alpha4c-MetEAEHGFIntegrinMSNeuroinflammationT lymphocytesTransmigration

Identifiers

PMID35488271
PMCPMC9052663
OpenAlexW4225163160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.