ArticleBMC plant biology2022
Metabolome and transcriptome profiling unveil the mechanisms of light-induced anthocyanin synthesis in rabbiteye blueberry (vaccinium ashei: Reade).
Article in BMC plant biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 64 citations in OpenAlex.
- Supplemental Lighting Enhances Blueberry Fruit Quality and Flavonoid Accumulation Associated withPlants (Basel, Switzerland) · 2026Article
- Anthocyanin biosynthesis in blueberry is regulated by light and abscisic acid signaling via a VcABF2-miR156-VcSPL9 feedback loop.The New phytologist · 2026Article
- Effects of exogenous polyamines and their synthesis inhibitors on the growth and development of blueberry fruits.BMC plant biology · 2026Article
- Regulatory mechanisms and multidimensional applications of blueberry anthocyanins: a review of current gaps and future directions.Engineering in life sciences · 2026Review
- Leaf bidirectional reflectance distribution function (BRDF) prediction with phenotypic traits in four species: Development of a novel measuring and analyzing framework.Plant phenomics (Washington, D.C.) · 2025Article
- Multi-Omics Decoding of Potential Microbial-Genetic Synergy Underlying Polysaccharide and Glycosidic Polymer Biosynthesis in Two Cultivars ofMetabolites · 2025Article
- Integrative metabolomic and transcriptomic analysis provides insight into the mechanism of pigmentation in potato tuber eyes.BMC plant biology · 2025Article
- Three bilberry bHLHs of subgroup IIIf play divergent roles in fruit anthocyanin and flavonoid biosynthesis.Scientific reports · 2025Article
- Metabolome and transcriptome profiling reveals light-induced anthocyanin biosynthesis and anthocyanin-related key transcription factors in Yam (Dioscorea Alata L.).BMC plant biology · 2025Article
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- Transcriptome and metabolome analysis reveals mechanism of light intensity modulating iridoid biosynthesis in Gentiana macrophylla Pall.BMC plant biology · 2024Article
- Identification and Characterization of the Glutathione S-Transferase Gene Family in Blueberry (Plants (Basel, Switzerland) · 2024Article
- Integrated Untargeted Metabolome, Full-Length Sequencing and Transcriptome Analyses Reveal the Mechanism of Flavonoid Biosynthesis in Blueberry (International journal of molecular sciences · 2024Article
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- Unraveling verticillium wilt resistance: insight from the integration of transcriptome and metabolome in wild eggplant.Frontiers in plant science · 2024Article
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- Genome-Wide Identification of Bilberry WRKY Transcription Factors: Go Wild and Duplicate.Plants (Basel, Switzerland) · 2023Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBlueberry is one of the most important fruit crops worldwide. Anthocyanin is an important secondary metabolites that affects the appearance and nutritive quality of blueberries. However, few studies have focused on the molecular mechanism underlying anthocyanin accumulation induced by light intensity in blueberries.
resultsThe metabolic analysis revealed that there were 134 significantly changed metabolites in the natural light compared to the control, and flavone, flavonol, and anthocyanins were the most significantly increased. Transcriptome analysis found 6 candidate genes for the anthocyanin synthesis pathway. Quantitative reverse transcription PCR (qRT-PCR) results confirmed changes in the expression levels of genes encoding metabolites involved in the flavonoid synthesis pathways. The flavonoid metabolic flux in the light intensity-treatment increased the accumulation of delphinidin-3-O-arabinoside compared to under the shading-treatment. Furthermore, we performed qRT-PCR analysis of anthocyanin biosynthesis genes and predicted that the gene of VcF3'5'H4 may be a candidate gene for anthocyanin accumulation and is highly expressed in light intensity-treated fruit. Through the co-expression analysis of transcription factors and anthocyanin synthesis pathway genes, we found that the VcbHLH004 gene may regulate VcF3'5'H4, and then we transformed VcbHLH004 heterologously into tomato to verify its function.
conclusionThese results provide novel insights into light intensity regulation of blueberry anthocyanin accumulation and represent a valuable data set to guide future functional studies and blueberry breeding.
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