Evidence map›Paper›PMID 35488105›Full record

ArticleBasic research in cardiology2022

Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms.

V Biasci, L Santini, G A Marchal, S Hussaini, C Ferrantini, R Coppini, L M Loew, S Luther, M Campione, C Poggesi and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Basic research in cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Optogenetics meets physiology.Pflugers Archiv : European journal of physiology · 2023
    Article
  12. Article
  13. In silico optical modulation of spiral wave trajectories in cardiac tissue.Pflugers Archiv : European journal of physiology · 2023
    Article
  14. Review
  15. Review
  16. Near-infrared voltage-sensitive dyes based on chromene donor.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals.American journal of physiology. Heart and circulatory physiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 6 countries.

V BiasciEuropean Laboratory for Non-Linear Spectroscopy - LENS, Sesto Fiorentino, Italy. biasci@lens.unifi.it.
L SantiniDepartment of Neurology, Psychology, Drug Sciences and Child Health, University of Florence, Florence, Italy.
G A MarchalEuropean Laboratory for Non-Linear Spectroscopy - LENS, Sesto Fiorentino, Italy.
S HussainiMax Planck Institute for Dynamics and Self-Organization, Gottingen, Germany.
C FerrantiniEuropean Laboratory for Non-Linear Spectroscopy - LENS, Sesto Fiorentino, Italy.
R CoppiniDepartment of Neurology, Psychology, Drug Sciences and Child Health, University of Florence, Florence, Italy.
L M LoewCenter for Cell Analysis and Modeling, University of Connecticut, Farmington, CT, USA.
S LutherMax Planck Institute for Dynamics and Self-Organization, Gottingen, Germany.
M CampioneInstitute of Neuroscience (IN-CNR) and Department of Biomedical Science, University of Padua, Padua, Italy.
C PoggesiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
F S PavoneEuropean Laboratory for Non-Linear Spectroscopy - LENS, Sesto Fiorentino, Italy.
E CerbaiEuropean Laboratory for Non-Linear Spectroscopy - LENS, Sesto Fiorentino, Italy.
G BubDepartment of Physiology, McGill University, Montreal, Canada.
L SacconiEuropean Laboratory for Non-Linear Spectroscopy - LENS, Sesto Fiorentino, Italy. leonardo.sacconi@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0002-9320-5085
University of Florence · ITMax Planck Institute for Dynamics and Self-Organization · DEEuropean Theoretical Spectroscopy Facility · BEMcGill University · CAUniversity of Connecticut · USUniversity of Freiburg · DEUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac action potential (AP) shape and propagation are regulated by several key dynamic factors such as ion channel recovery and intracellular Ca

Indexed as

OptogeneticsTachycardia, VentricularAction PotentialsAnimalsLightingMiceMyocytes, CardiacCardiac alternansOptogeneticsVentricular tachycardiasVoltage imaging

Identifiers

PMID35488105
PMCPMC9054908
OpenAlexW4225128256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.