Evidence map›Paper›PMID 35487699›Full record

ArticleNeurology2022

Clinical Reasoning: A 77-Year-Old Man With Involuntary Movements, Sleep Changes, Falls, Bulbar Symptoms, and Cognitive Complaints.

Toni Qian Cao, Glenn R Harris, Christina M Lineback, Leonard L Sokol, Niccolo Mencacci, Puneet Opal

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Toni Qian CaoFrom the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL. toni.cao1@nm.org.
Glenn R HarrisFrom the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Christina M LinebackFrom the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0003-2048-333X
Leonard L SokolFrom the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Niccolo MencacciFrom the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Puneet OpalFrom the Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Northwestern University · US

Funding

Research Education ComponentP30AG072931 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ana Marie Daugherty · 2021 to 2026
$26.5M
Understanding the Cellular Basis of Movement DisordersR01NS082351 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Puneet Opal · 2013 to 2026
$6.2M
Preclinical Development of Antisense Oligonucleotide Therapy for Spinocerebellar Ataxia Type 3U01NS106670 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCLOUGHLIN, HAYLEY SARAH, PAULSON, HENRY L · 2018 to 2021
$2.1M
NIA NIH HHS P30 AG072931NINDS NIH HHS R01 NS082351NINDS NIH HHS U01 NS106670
6 · The paper itself

Abstract

A 77-year-old-man presents with chorea, parasomnias, dysarthria and dysphagia, and cognitive issues. A broad workup reveals positive anti-IgLON5 antibody. This case report represents a textbook example of anti-IgLON5 syndrome.

Indexed as

ChoreaParasomniasAgedClinical ReasoningCognitionHumansSleep

Identifiers

PMID35487699
PMCPMC9259088
OpenAlexW4225248523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.