Evidence map›Paper›PMID 35487686›Full record

ReviewGenes & development2022

Roles of vimentin in health and disease.

Karen M Ridge, John E Eriksson, Milos Pekny, Robert D Goldman

Abstract readReview
In one paragraph

Review in Genes & development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

150 citing papers in PubMed.

  1. Trial
  2. Type III intermediate filaments as novel CoAlation targets.Redox report : communications in free radical research · 2026
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  4. Observational
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90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karen M Ridge *Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, Illinois 60611, USA.ORCID 0000-0001-7784-0014
John E Eriksson *Cell Biology, Faculty of Science and Technology, Åbo Akademi University, FIN-20521 Turku, Finland.
Milos Pekny *Laboratory of Astrocyte Biology and CNS Regeneration, Center for Brain Repair, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, 413 90 Gothenburg, Sweden.ORCID 0000-0003-1607-8075
Robert D Goldman *Division of Pulmonary and Critical Care Medicine, Northwestern University, Chicago, Illinois 60611, USA.ORCID 0000-0003-0383-1435

Funding

Tissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GR Scott Budinger · 2015 to 2026
$26.9M
The Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9M
Structural basis of the specific protein-protein interactions underlying IF assemP01GM096971 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DANUSER, GAUDENZ, GELFAND, VLADIMIR I · 2011 to 2021
$16.8M
Mechanobiology of Vimentin Intermediate Filaments in 3D Collective Cell MigrationR01GM140108 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GUO, MING, WONG, IAN Y · 2021 to 2025
$2.3M
Vimentin-mediated regulation of the inflammasome in acute lung injuryR01HL128194 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RIDGE, KAREN M · 2016 to 2019
$1.5M
NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL128194NIA NIH HHS P01 AG049665NIGMS NIH HHS P01 GM096971NIGMS NIH HHS R01 GM140108
6 · The paper itself

Abstract

More than 27 yr ago, the vimentin knockout (

Indexed as

Intermediate FilamentsAnimalsCell Physiological PhenomenaMiceVimentinVimentinVim protein, mouseintermediate filamentsvimentinvimentin-null mouse

Identifiers

PMID35487686
PMCPMC9067405

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.